2. Epigenetics
  3. Epigenetic Reader Domain
  4. UNC1021

UNC1021 is a selective L3MBTL3 inhibitor with an IC50 of 0.048 μM.

For research use only. We do not sell to patients.

UNC1021 Chemical Structure

UNC1021 Chemical Structure

CAS No. : 1322591-19-4

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Based on 1 publication(s) in Google Scholar

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Description

UNC1021 is a selective L3MBTL3 inhibitor with an IC50 of 0.048 μM[1].

IC50 & Target

IC50: 0.048 μM (L3MBTL3), 2.9 μM (L3MBTL1)[1]
Molecular Weight

438.61

Formula

C26H38N4O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1CCC(N2CCCC2)CC1)C3=CC=C(C(N4CCC(N5CCCC5)CC4)=O)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 9.09 mg/mL (20.72 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2799 mL 11.3996 mL 22.7993 mL
5 mM 0.4560 mL 2.2799 mL 4.5599 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2799 mL 11.3996 mL 22.7993 mL 56.9982 mL
5 mM 0.4560 mL 2.2799 mL 4.5599 mL 11.3996 mL
10 mM 0.2280 mL 1.1400 mL 2.2799 mL 5.6998 mL
15 mM 0.1520 mL 0.7600 mL 1.5200 mL 3.7999 mL
20 mM 0.1140 mL 0.5700 mL 1.1400 mL 2.8499 mL
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UNC1021 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UNC10211322591-19-4UNC 1021UNC-1021Epigenetic Reader DomainInhibitorinhibitorinhibit

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