High-throughput screening (HTS) provides starting leading compounds in the adventure of developing a new drug. Compound libraries are powerful tools for drug discovery as well as biomedical research based on high-throughput screening. Having high quality compound libraries is a prerequisite for drug screening.

MedChemExpress compound screening service, combined with MedChemExpress Bioactive Compound Libraries, Diversity Libraries, and Fragment Libraries,provides a ‘One-Stop Compound Screening Platform’ for customers working on drug discovery, target discovery and validation, and other basic and translational research projects.

MedChemExpress ‘One-Stop Compound Screening Platform’ - A Bridge to Drug Discovery

  • 200+ bioactive compound libraries with 24,000+ bioactive compounds.

  • 22,000+ fragment compounds with high diversity and solubility.

  • 70,000+ lead-like compounds with diverse structures and filter PAINS.

  • Target- and phenotype-based drug screening service.

  • Lead compound optimization.

Customize the Library Based on Your Needs

You can select compounds, form (powder/liquid), size and plate map depending on your requirements.

  • Specific Compounds
  • Quantities
  • Plate Map
  • Concentration
  • Form (Solid or Solution)
Custom Compound Libraries Price List
Compound Number 30μL/ per compound 50μL/ per compound 100μL/ per compound 200μL/ per compound
200-999 $ 3.2 $ 4.4 $ 6.4 $ 10
1000-4999 $ 2.6 $ 3.6 $ 5 $ 7
5000-9999 $ 2.4 $ 3.4 $ 4.5 $ 6.2
10000+ $ 2.2 $ 3.2 $ 4 $ 5.8
Tips:

This price is specifically for Multiple-well Plate screening libraries. (Total Price= N* Unit Price)

The actual availability of the product will be confirmed after verification.

8-Channel Handheld Screw Cap Decapper

  • Easy Operation

  • Suitable for Various Types of Screw Captubes

  • Rechargeable for Convenient and Quick Use

  • Dual-use: Capping and Decapping

MedChemExpress Compound Library Series

The following table only shows a representative list of best-selling libraries:

1. General Bioactive Library Series

Product Name Number of Compounds Description
Bioactive Compound Library 20,000+ Contains compounds with confirmed biological activities and clear targets. These compounds include natural products, innovative compounds, approved compounds, and clinical compounds.
Targeted Diversity Library 2,300+ The targeted diversity library covers more than 1,000 targets and isoforms, such as GPCRs, Ion channel, kinases, etc. 1-3 compounds with high potency and selectivity were carefully selected for each target and isoform.
Novel Bioactive Compound Library 1,200+ All compounds are structurally novel and bioactivity diverse which makes it easier to discover new lead compounds.

2. Drug Repurposing Library Series

Product Name Number of Compounds Description
FDA-Approved Drug Library 3,000+ Contains compounds that have completed preclinical and clinical studies. All compounds have good bioactivity, safety and bioavailability characteristics.
Clinical Compound Library 2,600+ Contains clinical compounds that refer to various research areas including anti-cancer, anti-infection, anti-inflammation, nervous disease.
Drug Repurposing Compound Library 5,000+ Contains approved drugs and passed phase Ⅰclinical drugs, which have been completed preclinical and clinical studies.

3. Natural Product Library Series

Product Name Number of Compounds Description
Natural Product Library 4,700+ A unique collection of natural compounds that contain saccharides and glycosides, phenylpropanoids, quinones, flavonoids, steroids, etc.
Human Endogenous Metabolite Compound Library 1,000+ A unique collection of human endogenous metabolites, all of which are derived from human issues.
Gut Microbial Metabolite Library 5,000+ Contains compounds derived from gut microbiomes for high-throughput screening (HTS) and high-content screening (HCS).

4. Disease-Related Library Series

For Cancer Research
Product Name Number of Compounds Description
Anti-Cancer Compound Library 7,900 Compounds with known anticancer activity or target cancer-related pathway.
Anti-Lung Cancer Compound Library 1,900+ Compounds with identified or potential anti-lung cancer activity.
For Neurological Disease Research
Product Name Number of Compounds Description
Neurodegenerative Disease-related Compound Library 2,300+ Compounds with anti-neurodegenerative diseases activities or target the unique targets of neurodegenerative diseases.
Anti-Alzheimer's Disease Compound Library 1,400+ Compounds with anti-Alzheimer’s Disease activities or target the unique targets of AD.
For Infection-Related Research
Product Name Number of Compounds Description
Anti-Infection Compound Library 3,000+ A unique collection of anti-infective compounds with anti-bacterial, anti-viral, anti-fungal and anti-parasite activities.
Antiviral Compound Library 1,300+ Anti-virus compounds that target several viruses, including SARS-CoV, HBV, HCV, HIV, HSV, influenza virus, etc.
For other Disease Research
Product Name Number of Compounds Description
Anti-Aging Natural Product Library 200+ A unique collection of natural products with identified anti-aging activity.
Immunology/Inflammation Compound Library 5,200+ Compounds targeting immunology/inflammation-related target such as CCR, COX, IRAK, MyD88, PDE, TLR, etc.

5. Signaling Pathway or Protein Family Library Series

Product Name Number of Compounds Description
Cell Cycle/DNA Damage Compound Library 2,000+ Compounds target cell cycle or DNA damage related targets such as CDK, ROCK, Aurora Kinase, ATM/ATR, DNA-PK, DNA/RNA Synthesis, etc.
Kinase Inhibitor Library 2,700+ Contains compounds target protein kinases, lipid kinases, carbohydrate kinases, and etc.
Mitochondria-Targeted Compound Library 900+ A unique collection of compounds that mainly target mitochondrial metabolism, ATP synthase, mitophagy, ROS, etc.

6.According to Product Features or Structures Series

Product Name Number of Compounds Description
CNS-Penetrant Compound Library 900+ A unique collection of compounds with confirmed CNS-penetrant property.
Covalent Screening Library 1,700+ Contains identified covalent inhibitors and compounds with covalent reaction groups as warheads, such as acrylamides, alkyl halides, epoxides, etc.

7.Fragment Libraries

Product Name Number of Compounds Description
Fragment Library 22,000+ A unique collection of fragment compounds, all of which obey the “Rule of Three (RO3) ”. This library is an important source of lead-like drugs.
Cysteine Targeted Covalent Fragment Library 3,200+ Fragments containing covalent warheads that target cysteine. These warheads include Acrylamides, Chloroacetamides, Acrylonitrile, etc.

8.Diversity Compound Library

Product Name Number of Compounds Description
50K Diversity Library 50,000 There are 36,857 unique scaffolds.Compounds in the library are novel, Lead-like, diverse, and encompass a rich chemical space.
5K Scaffold Library 5,000 Each compound represents a distinct scaffold, ensuring maximum diversity within the library.
Natural Product-like Library 5,000 Each molecule in the library with a Natural-likeness scoring > -2,and contains a key scaffold found in natural products (40+) or a Tanimoto similarity coefficient with natural products greater than 0.6.
Applications of High-throughput Screening

  • Drug Repurposing

  • New Drug Development

  • Identifying Tool Compounds

  • Target Validation

  • Mechanism Research

  • Assay Development

Publications Citing Use of MedChemExpress Compound Libraries
Please Note

1. This promotion starts on 08/01/2024 for North America only.

2. This activity is not to be used in conjunction with other promotions.

3. This price is specifically for Multiple-well Plate screening libraries. (Total Price= N* Unit Price)

4. The actual availability of the product will be confirmed after verification.

5. 30% off on 8-Channel Handheld Screw Cap Decapper.

6. No participation if the product is purchased on the third party or other platform.

7. All rights of interpretation belong to MedChemExpress (MCE).