2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Viloxazine hydrochloride

Viloxazine hydrochloride  (Synonyms: Viloxazin hydrochloride; Emovit hydrochloride)

Cat. No.: HY-125784 Purity: 98.94%
SDS COA Handling Instructions

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Viloxazine hydrochloride is the hydrochloride salt form of Viloxazine (HY-W380450). Viloxazine (Viloxazin) hydrochloride is a norepinephrine reuptake inhibitor and a potent 5-HT2C agonist agent and 5-HT2B antagonist, EC50 for 5-HT2C b> is 32 μM, and the IC50 for 5-HT2B is 27 μM. Viloxazine hydrochloride's mechanism of action primarily involves serotonergic and noradrenergic pathways. Viloxazine hydrochloride is used in antidepressant research.

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Viloxazine hydrochloride Chemical Structure

Viloxazine hydrochloride Chemical Structure

CAS No. : 35604-67-2

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Based on 1 publication(s) in Google Scholar

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Viloxazine hydrochloride Related Antibodies

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Description

Viloxazine hydrochloride is the hydrochloride salt form of Viloxazine (HY-W380450). Viloxazine (Viloxazin) hydrochloride is a norepinephrine reuptake inhibitor and a potent 5-HT2C agonist agent and 5-HT2B antagonist, EC50 for 5-HT2C b> is 32 μM, and the IC50 for 5-HT2B is 27 μM. Viloxazine hydrochloride's mechanism of action primarily involves serotonergic and noradrenergic pathways. Viloxazine hydrochloride is used in antidepressant research[1][2].

Molecular Weight

273.76

Formula

C13H20ClNO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCOC1=C(OCC2OCCNC2)C=CC=C1.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (121.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6528 mL 18.2642 mL 36.5283 mL
5 mM 0.7306 mL 3.6528 mL 7.3057 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.94%

SDS (393 KB)

COA (250 KB) HNMR (243 KB) LCMS (87 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6528 mL 18.2642 mL 36.5283 mL 91.3209 mL
5 mM 0.7306 mL 3.6528 mL 7.3057 mL 18.2642 mL
10 mM 0.3653 mL 1.8264 mL 3.6528 mL 9.1321 mL
15 mM 0.2435 mL 1.2176 mL 2.4352 mL 6.0881 mL
20 mM 0.1826 mL 0.9132 mL 1.8264 mL 4.5660 mL
25 mM 0.1461 mL 0.7306 mL 1.4611 mL 3.6528 mL
30 mM 0.1218 mL 0.6088 mL 1.2176 mL 3.0440 mL
40 mM 0.0913 mL 0.4566 mL 0.9132 mL 2.2830 mL
50 mM 0.0731 mL 0.3653 mL 0.7306 mL 1.8264 mL
60 mM 0.0609 mL 0.3044 mL 0.6088 mL 1.5220 mL
80 mM 0.0457 mL 0.2283 mL 0.4566 mL 1.1415 mL
100 mM 0.0365 mL 0.1826 mL 0.3653 mL 0.9132 mL
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Viloxazine hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Viloxazine35604-67-2ViloxazinEmovit5-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorSerotonergicnoradrenergic5-HTdepressionInhibitorinhibitorinhibit

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