2. Metabolic Enzyme/Protease Anti-infection Apoptosis
  3. Pyruvate Kinase Bacterial Fungal Apoptosis
  4. Vitamin K5 hydrochloride

Vitamin K5 hydrochloride is a photosensitizer and a antimicrobial agent. Vitamin K5 hydrochloride is a specific PKM2 inhibitor with IC50 values of 28, 191 and 120 μM for PKM2, PKM1 and PKL. Vitamin K5 hydrochloride induces apoptosis of colon 26 cells. Vitamin K5 hydrochloride can be used for the research of infection and cancer, and it also can be used as a preservative for pharmaceuticals, foods, and beverages.

For research use only. We do not sell to patients.

Vitamin K5 hydrochloride Chemical Structure

Vitamin K5 hydrochloride Chemical Structure

CAS No. : 130-24-5

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50 mg USD 130 In-stock
100 mg USD 199 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Vitamin K5 hydrochloride:

Vitamin K5 hydrochloride Related Antibodies

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Description

Vitamin K5 hydrochloride is a photosensitizer and a antimicrobial agent. Vitamin K5 hydrochloride is a specific PKM2 inhibitor with IC50 values of 28, 191 and 120 μM for PKM2, PKM1 and PKL. Vitamin K5 hydrochloride induces apoptosis of colon 26 cells. Vitamin K5 hydrochloride can be used for the research of infection and cancer, and it also can be used as a preservative for pharmaceuticals, foods, and beverages[1][2][3].

In Vitro

Vitamin K5 (0-1600 μM) hydrochloride increases the antibacterial effects of UVA irradiation to Escherichia coli, Bacillus cereus, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis and Klebsiella pneumoniae[1].
Vitamin K5 (250-1000 μM) hydrochloride generates superoxide anion radical and hydroxyl radical with a fixed UVA dose of 2.9 J cm-2[1].
Vitamin K5 (0-100 μM; 1 h) hydrochloride dose-dependently inhibits the cellular glucose consumption and lactate production[2].
Vitamin K5 hydrochloride dose-dependently suppresses the proliferation of colon 26 cells[3].
Vitamin K5 hydrochloride induces cell apoptosis and increases activity of caspase-3 in colon 26 cells[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Vitamin K5 hydrochloride Related Antibodies
Molecular Weight

209.68

Formula

C11H12ClNO
CAS No.
Appearance

Solid

Color

Light yellow to light brown

SMILES

OC1=C2C=CC=CC2=C(N)C=C1C.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (596.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7693 mL 23.8463 mL 47.6926 mL
5 mM 0.9539 mL 4.7693 mL 9.5385 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.7693 mL 23.8463 mL 47.6926 mL 119.2316 mL
5 mM 0.9539 mL 4.7693 mL 9.5385 mL 23.8463 mL
10 mM 0.4769 mL 2.3846 mL 4.7693 mL 11.9232 mL
15 mM 0.3180 mL 1.5898 mL 3.1795 mL 7.9488 mL
20 mM 0.2385 mL 1.1923 mL 2.3846 mL 5.9616 mL
25 mM 0.1908 mL 0.9539 mL 1.9077 mL 4.7693 mL
30 mM 0.1590 mL 0.7949 mL 1.5898 mL 3.9744 mL
40 mM 0.1192 mL 0.5962 mL 1.1923 mL 2.9808 mL
50 mM 0.0954 mL 0.4769 mL 0.9539 mL 2.3846 mL
60 mM 0.0795 mL 0.3974 mL 0.7949 mL 1.9872 mL
80 mM 0.0596 mL 0.2981 mL 0.5962 mL 1.4904 mL
100 mM 0.0477 mL 0.2385 mL 0.4769 mL 1.1923 mL
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Vitamin K5 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vitamin K5130-24-5Vitamin K 5Vitamin K-5Pyruvate KinaseBacterialFungalApoptosisInhibitorinhibitorinhibit

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