2. Metabolic Enzyme/Protease
  3. Cathepsin
  4. Z-Gly-Pro-Arg-AMC hydrochloride

Z-Gly-Pro-Arg-AMC hydrochloride 

Cat. No.: HY-P4217 Purity: 98.60%
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Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Z-Gly-Pro-Arg-AMC hydrochloride Chemical Structure

Z-Gly-Pro-Arg-AMC hydrochloride Chemical Structure

CAS No. : 201928-42-9

Size Price Stock Quantity
1 mg USD 70 In-stock
5 mg USD 175 In-stock
10 mg USD 280 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Z-Gly-Pro-Arg-AMC hydrochloride Related Antibodies

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Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S

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Description

Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity[1][2].

Molecular Weight

656.13

Formula

C31H38ClN7O7
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Z-Gly-Pro-Arg-AMC
Sequence Shortening

Z-GPR-AMC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (152.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5241 mL 7.6204 mL 15.2409 mL
5 mM 0.3048 mL 1.5241 mL 3.0482 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5241 mL 7.6204 mL 15.2409 mL 38.1022 mL
5 mM 0.3048 mL 1.5241 mL 3.0482 mL 7.6204 mL
10 mM 0.1524 mL 0.7620 mL 1.5241 mL 3.8102 mL
15 mM 0.1016 mL 0.5080 mL 1.0161 mL 2.5401 mL
20 mM 0.0762 mL 0.3810 mL 0.7620 mL 1.9051 mL
25 mM 0.0610 mL 0.3048 mL 0.6096 mL 1.5241 mL
30 mM 0.0508 mL 0.2540 mL 0.5080 mL 1.2701 mL
40 mM 0.0381 mL 0.1905 mL 0.3810 mL 0.9526 mL
50 mM 0.0305 mL 0.1524 mL 0.3048 mL 0.7620 mL
60 mM 0.0254 mL 0.1270 mL 0.2540 mL 0.6350 mL
80 mM 0.0191 mL 0.0953 mL 0.1905 mL 0.4763 mL
100 mM 0.0152 mL 0.0762 mL 0.1524 mL 0.3810 mL
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Z-Gly-Pro-Arg-AMC hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Z-Gly-Pro-Arg-AMC201928-42-9Cathepsincathepsin KtrypsinsubstrateInhibitorinhibitorinhibit

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