2. Others Membrane Transporter/Ion Channel Neuronal Signaling Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds GABA Receptor Endogenous Metabolite
  4. γ-Aminobutyric acid-13C4

γ-Aminobutyric acid-13C4  (Synonyms: 4-Aminobutyric acid-13C4)

Cat. No.: HY-N0067S3 Purity: ≥99.0%
COA Handling Instructions

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γ-Aminobutyric acid-13C4 is the 13C-labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].

For research use only. We do not sell to patients.

γ-Aminobutyric acid-<sup>13</sup>C<sub>4</sub> Chemical Structure

γ-Aminobutyric acid-13C4 Chemical Structure

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1 mg USD 600 In-stock
5 mg USD 1500 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of γ-Aminobutyric acid-13C4:

γ-Aminobutyric acid-13C4 Related Antibodies

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Description

γ-Aminobutyric acid-13C4 is the 13C-labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

γ-Aminobutyric acid-13C4 Related Antibodies
Molecular Weight

107.09

Formula

13C4H9NO2
Unlabeled CAS

56-12-2
Appearance

Solid

Color

White to off-white

SMILES

O=[13C](O)[13CH2][13CH2][13CH2]N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (466.90 mM)

H2O : ≥ 50 mg/mL (466.90 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 9.3379 mL 46.6897 mL 93.3794 mL
5 mM 1.8676 mL 9.3379 mL 18.6759 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

COA (244 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 9.3379 mL 46.6897 mL 93.3794 mL 233.4485 mL
5 mM 1.8676 mL 9.3379 mL 18.6759 mL 46.6897 mL
10 mM 0.9338 mL 4.6690 mL 9.3379 mL 23.3449 mL
15 mM 0.6225 mL 3.1126 mL 6.2253 mL 15.5632 mL
20 mM 0.4669 mL 2.3345 mL 4.6690 mL 11.6724 mL
25 mM 0.3735 mL 1.8676 mL 3.7352 mL 9.3379 mL
30 mM 0.3113 mL 1.5563 mL 3.1126 mL 7.7816 mL
40 mM 0.2334 mL 1.1672 mL 2.3345 mL 5.8362 mL
50 mM 0.1868 mL 0.9338 mL 1.8676 mL 4.6690 mL
60 mM 0.1556 mL 0.7782 mL 1.5563 mL 3.8908 mL
80 mM 0.1167 mL 0.5836 mL 1.1672 mL 2.9181 mL
100 mM 0.0934 mL 0.4669 mL 0.9338 mL 2.3345 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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γ-Aminobutyric acid-13C4 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

γ-Aminobutyric acid-13C44-Aminobutyric acid-13C4Isotope-Labeled CompoundsGABA ReceptorEndogenous MetaboliteGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorInhibitorinhibitorinhibit

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