2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 3'-Deoxy-3'-fluoroadenosine

3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

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3'-Deoxy-3'-fluoroadenosine Chemical Structure

3'-Deoxy-3'-fluoroadenosine Chemical Structure

CAS No. : 75059-22-2

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Based on 1 publication(s) in Google Scholar

3'-Deoxy-3'-fluoroadenosine Related Antibodies

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Description

3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Cellular Effect
Cell Line Type Value Description References
MRC5 EC50
4.92 μM
Compound: 6
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability after 3 days by resazurin dye based fluorimetric analysis
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability after 3 days by resazurin dye based fluorimetric analysis
[PMID: 33667845]
Molecular Weight

269.24

Formula

C10H12FN5O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC[C@H]1O[C@@H](N(C=N2)C3=C2C(N)=NC=N3)[C@H](O)[C@@H]1F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Purity: 99.29%

SDS (393 KB)

COA (253 KB) HNMR (141 KB) LCMS (92 KB)

Handling Instructions (2659 KB)
References
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3'-Deoxy-3'-fluoroadenosine Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3'-Deoxy-3'-fluoroadenosine75059-22-2Nucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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Cat. No.:
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SAFETY DATA SHEET (SDS)

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