3’-O-(2-Methoxyethyl)guanosine

Cat. No.: HY-152493 Purity: 98.90%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

3’-O-(2-Methoxyethyl)guanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).

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3’-O-(2-Methoxyethyl)guanosine Chemical Structure

CAS No. : 256224-03-0

Size	Price	Stock	Quantity
Free Sample (0.1 - 0.5 mg)		Apply Now
25 mg	USD 40	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 65	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 105	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 215	In-stock	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

341.32

Formula

C₁₃H₁₉N₅O₆

CAS No.

256224-03-0

Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1[C@@H](OCCOC)[C@@H](O)[C@H](N(C=N2)C3=C2C(NC(N)=N3)=O)O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 87.5 mg/mL (256.36 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.9298 mL	14.6490 mL	29.2980 mL
5 mM	0.5860 mL	2.9298 mL	5.8596 mL
10 mM	0.2930 mL	1.4649 mL	2.9298 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.90%

Select Batch:

Data Sheet (272 KB) SDS (251 KB)

COA (249 KB) HNMR (252 KB) RP-HPLC (205 KB) LCMS (93 KB)

Handling Instructions (2659 KB)

References

[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.9298 mL	14.6490 mL	29.2980 mL	73.2450 mL
	5 mM	0.5860 mL	2.9298 mL	5.8596 mL	14.6490 mL
	10 mM	0.2930 mL	1.4649 mL	2.9298 mL	7.3245 mL
	15 mM	0.1953 mL	0.9766 mL	1.9532 mL	4.8830 mL
	20 mM	0.1465 mL	0.7325 mL	1.4649 mL	3.6623 mL
	25 mM	0.1172 mL	0.5860 mL	1.1719 mL	2.9298 mL
	30 mM	0.0977 mL	0.4883 mL	0.9766 mL	2.4415 mL
	40 mM	0.0732 mL	0.3662 mL	0.7325 mL	1.8311 mL
	50 mM	0.0586 mL	0.2930 mL	0.5860 mL	1.4649 mL
	60 mM	0.0488 mL	0.2442 mL	0.4883 mL	1.2208 mL
	80 mM	0.0366 mL	0.1831 mL	0.3662 mL	0.9156 mL
	100 mM	0.0293 mL	0.1465 mL	0.2930 mL	0.7325 mL