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  3. Disease Research Fields Plants Alkaloids
  4. Inflammation/Immunology other families Pyrrole Alkaloids
  5. 7-Acetyllycopsamine

7-Acetyllycopsamine, a pyrrolizidine alkaloid, is a mild hepatotoxin. 7-Acetyllycopsamine can induce liver inflammation in mice.

For research use only. We do not sell to patients.

7-Acetyllycopsamine Chemical Structure

7-Acetyllycopsamine Chemical Structure

CAS No. : 73544-48-6

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Based on 1 publication(s) in Google Scholar

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Description

7-Acetyllycopsamine, a pyrrolizidine alkaloid, is a mild hepatotoxin. 7-Acetyllycopsamine can induce liver inflammation in mice[1].

In Vivo

7-Acetyllycopsamine (750 mg/kg; single dose) induces liver inflammation, detectable as significantly greater serum ALT (alanine transaminase) scores than controls in C57BL/6J male mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

341.40

Formula

C17H27NO6
CAS No.
SMILES

CC(C)[C@@]([C@@H](O)C)(O)C(OCC1=CCN2[C@@]1([H])[C@H](OC(C)=O)CC2)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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7-Acetyllycopsamine Related Classifications

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Help & FAQs
  • Why are the cells in poor condition after PolyFast transfection?

    PolyFast has certain cytotoxicity, and it is normal for cell viability to decrease after transfection. Cells with a density of 70-90%, exponential phase, and a survival rate greater than 90% can be used for transfection.

  • Can PolyFast be used to transduce RNA?

    Yes, RNA transfection can be performed by referring to the DNA transfection method.

  • Can I use complete medium for transfection?

    No, serum and antibiotics will affect the stability of the transfection complex. It is recommended to use a basal culture medium that does not contain serum or antibiotics.

  • Do I need to change the culture medium after transfection?

    If necessary, the culture medium containing serum and antibiotics can be replaced 6 hours after transfection.

  • Can PolyFast be used to transfect suspension cells?

    Generally, it is recommended that you use a transfection reagent specifically for suspension cells. We have not verified the transfection effect of suspension cells yet. If you want to use this kit to transfect suspension cells, you can try to reduce the shaking speed after transfection to promote full contact between the PolyFast-DNA complex and the cells, increase the uptake rate, and avoid cell sedimentation, aggregation or hypoxia. After transfection for 6 hours, you can increase the shaking speed to the normal speed.

Keywords:

7-Acetyllycopsamine73544-48-6Otherspyrrolizidinealkaloid,hepatotoxinliverinflammationInhibitorinhibitorinhibit

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