benzyl (tert-Butoxycarbonyl)-L-leucyl-L-phenylalaninate

Name: benzyl (tert-Butoxycarbonyl)-L-leucyl-L-phenylalaninate
Brand: MedChemExpress
SKU: HY-79861
Rating: 4.5 (1 reviews)

Cat. No.: HY-79861: FAQs
Data Sheet SDS Handling Instructions

Molarity Calculator

benzyl (tert-Butoxycarbonyl)-L-leucyl-L-phenylalaninate is a phenylalanine derivative.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

benzyl (tert-Butoxycarbonyl)-L-leucyl-L-phenylalaninate Chemical Structure

CAS No. : 70637-26-2

Size	Price	Stock	Quantity
Free Sample (0.1 - 0.5 mg)		Apply Now
50 mg	USD 140	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 220	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 395	In-stock	Estimated Time of Arrival: December 31
1 g	USD 890	In-stock	Estimated Time of Arrival: December 31
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10 g		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

benzyl (tert-Butoxycarbonyl)-L-leucyl-L-phenylalaninate is a phenylalanine derivative^[1].

In Vitro

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

468.59

Formula

C₂₇H₃₆N₂O₅

CAS No.

70637-26-2

Appearance

Solid

Color

White to light yellow

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (213.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1341 mL	10.6703 mL	21.3406 mL
5 mM	0.4268 mL	2.1341 mL	4.2681 mL
10 mM	0.2134 mL	1.0670 mL	2.1341 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (5.34 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Data Sheet (271 KB) SDS (393 KB) Handling Instructions (2659 KB)

References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-863. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.1341 mL	10.6703 mL	21.3406 mL	53.3515 mL
	5 mM	0.4268 mL	2.1341 mL	4.2681 mL	10.6703 mL
	10 mM	0.2134 mL	1.0670 mL	2.1341 mL	5.3352 mL
	15 mM	0.1423 mL	0.7114 mL	1.4227 mL	3.5568 mL
	20 mM	0.1067 mL	0.5335 mL	1.0670 mL	2.6676 mL
	25 mM	0.0854 mL	0.4268 mL	0.8536 mL	2.1341 mL
	30 mM	0.0711 mL	0.3557 mL	0.7114 mL	1.7784 mL
	40 mM	0.0534 mL	0.2668 mL	0.5335 mL	1.3338 mL
	50 mM	0.0427 mL	0.2134 mL	0.4268 mL	1.0670 mL
	60 mM	0.0356 mL	0.1778 mL	0.3557 mL	0.8892 mL
	80 mM	0.0267 mL	0.1334 mL	0.2668 mL	0.6669 mL
	100 mM	0.0213 mL	0.1067 mL	0.2134 mL	0.5335 mL