1. Antibody-drug Conjugate/ADC Related
  2. ADC Cytotoxin
  3. 7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin)

7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin) 

Cat. No.: HY-156513 Purity: 98.88%
COA Handling Instructions

7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin) is a Camptothecin (HY-16560) analogue. 7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin) is a ADC cytotoxin that can be used for synthesis of ADCs, and for cancer research.

For research use only. We do not sell to patients.

7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin) Chemical Structure

7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin) Chemical Structure

CAS No. : 2873460-17-2

Size Price Stock Quantity
5 mg USD 790 In-stock
10 mg USD 1190 In-stock
25 mg USD 2266 In-stock
50 mg USD 3400 In-stock
100 mg   Get quote  
200 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Description

7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin) is a Camptothecin (HY-16560) analogue. 7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin) is a ADC cytotoxin that can be used for synthesis of ADCs, and for cancer research[1].

Molecular Weight

497.47

Formula

C25H24FN3O7

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C1N2C(C(C(C2)=C(C3=C4)CNC(OCCO)=O)=NC3=CC(F)=C4C)=CC5=C1COC([C@]5(O)CC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (201.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0102 mL 10.0509 mL 20.1017 mL
5 mM 0.4020 mL 2.0102 mL 4.0203 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0102 mL 10.0509 mL 20.1017 mL 50.2543 mL
5 mM 0.4020 mL 2.0102 mL 4.0203 mL 10.0509 mL
10 mM 0.2010 mL 1.0051 mL 2.0102 mL 5.0254 mL
15 mM 0.1340 mL 0.6701 mL 1.3401 mL 3.3503 mL
20 mM 0.1005 mL 0.5025 mL 1.0051 mL 2.5127 mL
25 mM 0.0804 mL 0.4020 mL 0.8041 mL 2.0102 mL
30 mM 0.0670 mL 0.3350 mL 0.6701 mL 1.6751 mL
40 mM 0.0503 mL 0.2513 mL 0.5025 mL 1.2564 mL
50 mM 0.0402 mL 0.2010 mL 0.4020 mL 1.0051 mL
60 mM 0.0335 mL 0.1675 mL 0.3350 mL 0.8376 mL
80 mM 0.0251 mL 0.1256 mL 0.2513 mL 0.6282 mL
100 mM 0.0201 mL 0.1005 mL 0.2010 mL 0.5025 mL
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7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin)
Cat. No.:
HY-156513
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