2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis Nucleoside Antimetabolite/Analog
  4. 7-TFA-ap-7-Deaza-dA

7-TFA-ap-7-Deaza-dA is a modified nucleoside. 7-TFA-ap-7-Deaza-dA can be used in the synthesis of deoxyribonucleic acid or nucleic acid. 7-TFA-ap-7-Deaza-dA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

For research use only. We do not sell to patients.

7-TFA-ap-7-Deaza-dA Chemical Structure

7-TFA-ap-7-Deaza-dA Chemical Structure

CAS No. : 178420-75-2

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5 mg USD 51 In-stock
10 mg USD 85 In-stock
25 mg USD 170 In-stock
50 mg USD 255 In-stock
100 mg USD 383 In-stock
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Based on 1 publication(s) in Google Scholar

7-TFA-ap-7-Deaza-dA Related Antibodies

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Description

7-TFA-ap-7-Deaza-dA is a modified nucleoside. 7-TFA-ap-7-Deaza-dA can be used in the synthesis of deoxyribonucleic acid or nucleic acid. 7-TFA-ap-7-Deaza-dA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Molecular Weight

399.32

Formula

C16H16F3N5O4
CAS No.
Appearance

Solid

Color

Off-white to brown

SMILES

OC[C@@H]1[C@@H](O)C[C@H](N2C(N=CN=C3N)=C3C(C#CCNC(C(F)(F)F)=O)=C2)O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (626.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5043 mL 12.5213 mL 25.0426 mL
5 mM 0.5009 mL 2.5043 mL 5.0085 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5043 mL 12.5213 mL 25.0426 mL 62.6064 mL
5 mM 0.5009 mL 2.5043 mL 5.0085 mL 12.5213 mL
10 mM 0.2504 mL 1.2521 mL 2.5043 mL 6.2606 mL
15 mM 0.1670 mL 0.8348 mL 1.6695 mL 4.1738 mL
20 mM 0.1252 mL 0.6261 mL 1.2521 mL 3.1303 mL
25 mM 0.1002 mL 0.5009 mL 1.0017 mL 2.5043 mL
30 mM 0.0835 mL 0.4174 mL 0.8348 mL 2.0869 mL
40 mM 0.0626 mL 0.3130 mL 0.6261 mL 1.5652 mL
50 mM 0.0501 mL 0.2504 mL 0.5009 mL 1.2521 mL
60 mM 0.0417 mL 0.2087 mL 0.4174 mL 1.0434 mL
80 mM 0.0313 mL 0.1565 mL 0.3130 mL 0.7826 mL
100 mM 0.0250 mL 0.1252 mL 0.2504 mL 0.6261 mL
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7-TFA-ap-7-Deaza-dA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7-TFA-ap-7-Deaza-dA178420-75-2DNA/RNA SynthesisNucleoside Antimetabolite/AnalogInhibitorinhibitorinhibit

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