2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Isocitric acid

Isocitric acid is an endogenous metabolite present in Saliva and Cellular_Cytoplasm that can be used for the research of Alzheimer's Disease, Lewy Body Dementia and Anoxia.

For research use only. We do not sell to patients.

Isocitric acid Chemical Structure

Isocitric acid Chemical Structure

CAS No. : 320-77-4

Size Price Stock Quantity
1 mg USD 170 In-stock
5 mg USD 430 In-stock
10 mg USD 700 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of Isocitric acid:

Isocitric acid Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Isocitric acid

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Isocitric acid is an endogenous metabolite present in Saliva and Cellular_Cytoplasm that can be used for the research of Alzheimer's Disease, Lewy Body Dementia and Anoxia[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Isocitric acid Related Antibodies
Molecular Weight

192.12

Formula

C6H8O7
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(C(O)=O)C(C(O)=O)CC(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (520.51 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2051 mL 26.0254 mL 52.0508 mL
5 mM 1.0410 mL 5.2051 mL 10.4102 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.91%

COA (248 KB) HNMR (271 KB) LCMS (89 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.2051 mL 26.0254 mL 52.0508 mL 130.1270 mL
5 mM 1.0410 mL 5.2051 mL 10.4102 mL 26.0254 mL
10 mM 0.5205 mL 2.6025 mL 5.2051 mL 13.0127 mL
15 mM 0.3470 mL 1.7350 mL 3.4701 mL 8.6751 mL
20 mM 0.2603 mL 1.3013 mL 2.6025 mL 6.5064 mL
25 mM 0.2082 mL 1.0410 mL 2.0820 mL 5.2051 mL
30 mM 0.1735 mL 0.8675 mL 1.7350 mL 4.3376 mL
40 mM 0.1301 mL 0.6506 mL 1.3013 mL 3.2532 mL
50 mM 0.1041 mL 0.5205 mL 1.0410 mL 2.6025 mL
60 mM 0.0868 mL 0.4338 mL 0.8675 mL 2.1688 mL
80 mM 0.0651 mL 0.3253 mL 0.6506 mL 1.6266 mL
100 mM 0.0521 mL 0.2603 mL 0.5205 mL 1.3013 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Isocitric acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isocitric acid320-77-4Endogenous MetaboliteInhibitorinhibitorinhibit

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