Metaraminol tartrate (Synonyms: Metaradrine tartrate)

Cat. No.: HY-B1116 Purity: 99.90%: FAQs
Data Sheet SDS COA Handling Instructions

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Metaraminol tartrate?(Metaradrine tartrate) is an α-adrenergic agonist. Metaraminol tartrate is a sympathomimetic amine that directly and indirectly affects adrenergic receptors, with alpha effects being predominant.Metaraminol tartrate acts as a vasopressor agent.

For research use only. We do not sell to patients.

Metaraminol tartrate Chemical Structure

CAS No. : 33402-03-8

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 41	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 41	In-stock	Estimated Time of Arrival: December 31
Solid
50 mg	USD 38	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
200 mg	USD 79	In-stock	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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Other Forms of Metaraminol tartrate:

Metaraminol Get quote
Metaraminol (tartrate) (Standard) Get quote

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α adrenergic receptor β adrenergic receptor

Biological Activity
Purity & Documentation
References
Customer Review

Description

Metaraminol tartrate?(Metaradrine tartrate) is an α-adrenergic agonist^[1]. Metaraminol tartrate is a sympathomimetic amine that directly and indirectly affects adrenergic receptors, with alpha effects being predominant.Metaraminol tartrate acts as a vasopressor agent^[2].

IC₅₀ & Target

Adrenergic Receptor^[1]

In Vitro

Stimulation of α-adrenoceptors by metaraminol, a drug with properties similar to noradrenaline, caused acceleration of cell proliferation in colonie crypts but not in tumors^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Lethal endotoxin shock is prevented in six of the 10 animals studied by the simultaneous use of Metaraminol^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Ten adult dogs weighing between 7.8 and 13 kg^[2]
Dosage:	Solution containing 25 mg in 250 mL of 5 percent dextrose and water
Administration:	Intravenous infusion
Result:	Lethal endotoxin shock was prevented,

Molecular Weight

317.29

Formula

C₁₃H₁₉NO₈

CAS No.

33402-03-8

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)[C@H](O)[C@@H](O)C(O)=O.OC1=CC=CC([C@@H](O)[C@@H](N)C)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : ≥ 28 mg/mL (88.25 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1517 mL	15.7585 mL	31.5169 mL
5 mM	0.6303 mL	3.1517 mL	6.3034 mL
10 mM	0.3152 mL	1.5758 mL	3.1517 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.90%

Select Batch:

Data Sheet (280 KB) SDS (420 KB)

COA (258 KB) HNMR (258 KB) RP-HPLC (207 KB)

Handling Instructions (2659 KB)

References

[1]. C Tong, et al. The vascular mechanism of ephedrine's beneficial effect on uterine perfusion during pregnancy. Anesthesiology. 1992 May;76(5):792-8. [Content Brief]

[2]. WESLEY W. SPINK, et al. Evaluation of Plasma, Metaraminol, and Hydrocortisone in Experimental Endotoxm Shock.

[3]. P J Tutton, D H Barkla. The influence of adrenoceptor activity on cell proliferation in colonic crypt ipithelium and in colonic adenocarcinomata. Virchows Arch B Cell Pathol. 1977 Jun 24;24(2):139-46. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.1517 mL	15.7585 mL	31.5169 mL	78.7923 mL
	5 mM	0.6303 mL	3.1517 mL	6.3034 mL	15.7585 mL
	10 mM	0.3152 mL	1.5758 mL	3.1517 mL	7.8792 mL
	15 mM	0.2101 mL	1.0506 mL	2.1011 mL	5.2528 mL
	20 mM	0.1576 mL	0.7879 mL	1.5758 mL	3.9396 mL
	25 mM	0.1261 mL	0.6303 mL	1.2607 mL	3.1517 mL
	30 mM	0.1051 mL	0.5253 mL	1.0506 mL	2.6264 mL
	40 mM	0.0788 mL	0.3940 mL	0.7879 mL	1.9698 mL
	50 mM	0.0630 mL	0.3152 mL	0.6303 mL	1.5758 mL
	60 mM	0.0525 mL	0.2626 mL	0.5253 mL	1.3132 mL
	80 mM	0.0394 mL	0.1970 mL	0.3940 mL	0.9849 mL

Metaraminol tartrate Related Classifications

Endocrinology Cardiovascular Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Metaraminol33402-03-8MetaradrineAdrenergic ReceptorBeta ReceptoradrenergicvasopressorInhibitorinhibitorinhibit

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