2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (7205):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0172S
    Lithocholic acid-d4
    		99.72%
    Lithocholic acid-d4 is the deuterium labeled Lithocholic acid, which is a toxic secondary bile acid[1].
    Lithocholic acid-d<sub>4</sub>
  • HY-N0394S1
    L-Cystine-d4
    		≥98.0%
    L-Cystine-d4 is the deuterium labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.
    L-Cystine-d<sub>4</sub>
  • HY-Y1269S
    Ammonium chloride-15N
    		≥98.0%
    Ammonium chloride-15N is the 15N labeled Ammonium chloride (HY-Y1269). Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metabolic acidosis thus effecting enzymatic activity and influencing the process of biological system. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor.
    Ammonium chloride-<sup>15</sup>N
  • HY-B0322S
    Sulfamethoxazole-d4
    		99.56%
    Sulfamethoxazole-d4 is a deuterium labeled Sulfamethoxazole (Ro 4-2130). Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic.
    Sulfamethoxazole-d<sub>4</sub>
  • HY-W654288
    NAD+-d4
    		98.71%
    NAD+-d4 is the deuterium-labeled NAD+ (HY-B0445). NAD+-d4 is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
    NAD+-d<sub>4</sub>
  • HY-14608S3
    L-Glutamic acid-13C5,15N
    		≥98.0%
    L-Glutamic acid-13C5,15N is the 13C- and 15N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
    L-Glutamic acid-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N
  • HY-Y0966S1
    Glycine-d2
    		≥99.0%
    Glycine-d2 is the deuterium labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
    Glycine-d<sub>2</sub>
  • HY-132949S
    Decanoyl-L-carnitine-d3 chloride
    		99.94%
    Decanoyl-L-carnitine-d3 (chloride) is the deuterium labeled Decanoyl-L-carnitine chloride[1].
    Decanoyl-L-carnitine-d<sub>3</sub> chloride
  • HY-N0473S
    L-Tyrosine-d4
    		≥98.0%
    L-Tyrosine-d4 is a deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex[1].
    L-Tyrosine-d<sub>4</sub>
  • HY-W017462S
    Creatine-d5 monohydrate
    		99.93%
    Creatine-d5 (monohydrate) is the deuterium labeled Creatine monohydrate. Creatine monohydrate, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain[1].
    Creatine-d<sub>5</sub> monohydrate
  • HY-50767S
    Palbociclib-d8
    		99.84%
    Palbociclib-d8 is a deuterium labeled Palbociclib. Palbociclib is a selective and orally active CDK4 and CDK6 inhibitor with IC50s of 11 and 16 nM, respectively. Palbociclib has the potential for ER-positive and HER2-negative breast cancer research[1].
    Palbociclib-d<sub>8</sub>
  • HY-B0504S2
    Creatinine-d5
    		99.90%
    Creatinine-d5 is the deuterium labeled Creatinine. Creatinine (NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.
    Creatinine-d<sub>5</sub>
  • HY-W014423S4
    L-Histidine-d5 hydrochloride hydrate
    		99.63%
    L-Histidine-d5 (hydrochloride hydrate) is the deuterium labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
    L-Histidine-d<sub>5</sub> hydrochloride hydrate
  • HY-B2227BS1
    Lactate-d3 sodium
    		98.00%
    Lactate-d3 sodium (60% in water) is the deuterium labeled Lactate sodium (60% in water). Lactate sodium (60% in water) is the product of glycogenolysis and glycolysis. Lactate sodium (60% in water) functions in a variety of biochemical processes.
    Lactate-d<sub>3</sub> sodium
  • HY-A0181S1
    Adenosine monophosphate-15N5 dilithium
    		99.50%
    Adenosine monophosphate-15N5 dilithium is the 15N labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.
    Adenosine monophosphate-<sup>15</sup>N<sub>5</sub> dilithium
  • HY-D0857S
    HEPES-d18
    		99.90%
    HEPES-d18 is the deuterium labeled HEPES[1]. HEPES, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is also a potent inducer of lysosome biogenesis[2][3][4].
    HEPES-d<sub>18</sub>
  • HY-N0067S1
    γ-Aminobutyric acid-d2
    		99.72%
    γ-Aminobutyric acid-d2 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].
    γ-Aminobutyric acid-d<sub>2</sub>
  • HY-B0075S
    Melatonin-d4
    		≥99.0%
    Melatonin-d4 is deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Antioxidative and anti-inflammatory properties. Melatonin is a selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation.
    Melatonin-d<sub>4</sub>
  • HY-W099602S
    Dodecane-d26
    		99.83%
    Dodecane-d26 is the deuterium labeled Dodecane[1].
    Dodecane-d<sub>26</sub>
  • HY-B0015S
    Paclitaxel-d5
    		≥98.0%
    Paclitaxel-d5 is a deuterium-labeled Paclitaxel. Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization.
    Paclitaxel-d<sub>5</sub>