Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitor (1)

Isotope-Labeled Compounds Related Products (7211):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-Y0507S

DL-Serine-2,3,3-d₃		99.91%
DL-Serine-2,3,3-d₃ is the deuterium labeled DL-Serine. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV)[1].

HY-A0181BS

Adenosine monophosphate-¹³C₁₀,¹⁵N₅ disodium		98.7%
Adenosine monophosphate-¹³C₁₀,¹⁵N₅ (AMP-¹³C₁₀,¹⁵N₅) disodium is ¹³C and ¹⁵N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

HY-N0455AS1

L-Arginine-¹⁵N₄ hydrochloride		99.85%
L-Arginine-¹⁵N₄ (hydrochloride) is the ¹⁵N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis[1].

HY-B0445S

NAD⁺-¹³C₅ ammonium		98.89%
NAD+-13C5 (ammonium) is the ¹³C labled NAD+ (HY-B0445), with an ammonium.

HY-N0492S

α-Lipoic Acid-d₅
α-Lipoic Acid-d₅ is the deuterium labeled α-Lipoic Acid. α-Lipoic Acid is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation[1][2][3]. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells[4].

HY-104026S2

L-Kynurenine-d₄-1 hydrochloride		99.47%
L-Kynurenine-d₄-1 hydrochloride is the deuterium labeled L-Kynurenine (HY-104026). L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

HY-Y0966S3

Glycine-¹³C₂		99.10%
Glycine-¹³C₂ is the ¹³C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

HY-N0415S

Trigonelline-d₃ chloride		99.41%
Trigonelline-d₃ (chloride) is the deuterium labeled Trigonelline chloride. Trigonelline chloride, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee. Trigonelline chloride has anti-HSV-1 , antibacterial, and antifungal activities.

HY-N0771S2

L-Isoleucine-¹⁵N		98.00%
L-Isoleucine-15N is the 15N-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid. L-Isoleucine is an essential amino acid.

HY-Y0669S

Pipecolic acid-d₉		99.59%
Pipecolic acid-d₉ is the deuterium labeled Pipecolic acid. Pipecolic acid is a metabolite of lysine and an immunomodulator, which can induce systemic acquired resistance (SAR) in plants. Pipecolic acid inhibits ferroptosis in diabetic retinopathy through the YAP-GPX4 signaling pathway. Pipecolic acid can induce apoptosis in neuronal cells. In addition, Pipecolic acid can be used as a diagnostic marker for pyridoxin-dependent epilepsy.

HY-18569S3

3-Indoleacetic acid-d₇		≥99.00%
3-Indoleacetic acid-d₇ is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.

HY-10219S

Rapamycin-d₃
Rapamycin-d₃ is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC₅₀ of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.

HY-B0399S

L-Carnitine-d₉		≥99.0%
L-Carnitine-d₉ is the deuterium labeled L-Carnitine. L-Carnitine (Levocarnitine) is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2].

HY-B2227BS

Lactate-d₄ sodium		≥99.0%
Lactate-d₄ sodium (60% in water) is the deuterium labeled Lactate sodium (60% in water). Lactate sodium (60% in water) is the product of glycogenolysis and glycolysis. Lactate sodium (60% in water) functions in a variety of biochemical processes.

HY-134928AS

Pyridinium bisretinoid A2E-d₄ TFA
Pyridinium bisretinoid A2E-d₄ TFA is the deuterium-labeled Pyridinium bisretinoid A2E (HY-134928). Pyridinium bisretinoid A2E (A2E)is an initiator of blue-light-induced apoptosis. Photoactivation of Pyridinium bisretinoid A2E mediates autophagy and the production of reactive oxygen species.

HY-B0351S2

Taurine-¹³C₂,¹⁵N		98.60%
Taurine-¹³C₂,¹⁵N is the ¹³C- and ¹⁵N- labeled Taurine. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes[1][2][3].

HY-W010209S2

DL-Histidine-d₃		≥99.0%
DL-Histidine-d₃ is the deuterium labeled DL-Histidine.

HY-B2176S5

ATP-¹⁵N₅ dilithium		≥99.0%
ATP-¹⁵N₅ (Adenosine 5'-triphosphate-¹⁵N₅) dilithium is ¹⁵N labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.

HY-N0100S

Naringenin-d₄		99.88%
Naringenin-d₄ is the deuterated version of Naringenin (HY-N0100). Naringenin shows strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity[1].

HY-W017389S

Xanthine-¹³C,¹⁵N₂		≥98.0%
Xanthine-¹³C,¹⁵N₂ is a ¹⁵N-labeled and ¹³C-labled Xanthine (HY-W017389). Xanthine is a plant alkaloid with mild stimulant activity of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation.

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