1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Tetradecanoylcarnitine

Tetradecanoylcarnitine is a human carnitine involved in β-oxidation of long-chain fatty acids.

For research use only. We do not sell to patients.

Tetradecanoylcarnitine Chemical Structure

Tetradecanoylcarnitine Chemical Structure

CAS No. : 25597-07-3

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Based on 1 publication(s) in Google Scholar

Other Forms of Tetradecanoylcarnitine:

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Description

Tetradecanoylcarnitine is a human carnitine involved in β-oxidation of long-chain fatty acids.

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

371.55

Formula

C21H41NO4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCCCC(O[C@H](CC([O-])=O)C[N+](C)(C)C)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (269.14 mM; Need ultrasonic)

DMSO : 25 mg/mL (67.29 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6914 mL 13.4571 mL 26.9143 mL
5 mM 0.5383 mL 2.6914 mL 5.3829 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (6.73 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (6.73 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 2.6914 mL 13.4571 mL 26.9143 mL 67.2857 mL
5 mM 0.5383 mL 2.6914 mL 5.3829 mL 13.4571 mL
10 mM 0.2691 mL 1.3457 mL 2.6914 mL 6.7286 mL
15 mM 0.1794 mL 0.8971 mL 1.7943 mL 4.4857 mL
20 mM 0.1346 mL 0.6729 mL 1.3457 mL 3.3643 mL
25 mM 0.1077 mL 0.5383 mL 1.0766 mL 2.6914 mL
30 mM 0.0897 mL 0.4486 mL 0.8971 mL 2.2429 mL
40 mM 0.0673 mL 0.3364 mL 0.6729 mL 1.6821 mL
50 mM 0.0538 mL 0.2691 mL 0.5383 mL 1.3457 mL
60 mM 0.0449 mL 0.2243 mL 0.4486 mL 1.1214 mL
H2O 80 mM 0.0336 mL 0.1682 mL 0.3364 mL 0.8411 mL
100 mM 0.0269 mL 0.1346 mL 0.2691 mL 0.6729 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Tetradecanoylcarnitine
Cat. No.:
HY-113201
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