Anthraquinone 

Anthraquinone is used as a precursor for dye formation and agrochemicals, existing in different organisms, such as bacteria, fungi, plants, and some animals. Anthraquinone has biological activities: anticancer, antiinflammatory, diuretic, antiarthritic, antifungal, antibacterial, antimalarial and antioxidant. Anthraquinone also plays an important role in the primary metabolism of plants by acting on the electron transport chain through the inhibition of energy transfer in the photosynthetic process. Anthraquinone can intercalates into DNA and inhibits the topoisomerase II (topo II) enzyme, resulting in cell death via Apoptosis^[1][2][3][4].

Anthraquinone (0.2 mg/mL, 3 min) shows a strong antioxidant activity in vitro^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

208.21

C₁₄H₈O₂

84-65-1

Solid

Light yellow to yellow

O=C1C2=C(C=CC=C2)C(C3=CC=CC=C13)=O

Room temperature in continental US; may vary elsewhere.

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

• [1]. Diaz-Munoz G, et al. Anthraquinones: an overview[J]. Studies in natural products chemistry, 2018, 58: 313-338.

  [2]. Yen G C, Duh P D, Chuang D Y. Antioxidant activity of anthraquinones and anthrone[J]. Food chemistry, 2000, 70(4): 437-441.

  [3]. Andersen DO, et al. In vitro virucidal activity of selected anthraquinones and anthraquinone derivatives. Antiviral Res. 1991 Sep;16(2):185-96.  [Content Brief]

  [4]. Barnard D L, et al. Evaluation of the antiviral activity of anthraquinones, anthrones and anthraquinone derivatives against human cytomegalovirus[J]. Antiviral research, 1992, 17(1): 63-77.