2. Immunology/Inflammation
  3. STING
  4. Anti-inflammatory agent 70

Anti-inflammatory agent 70 (N-Me-SP23) is a STING protein degrader and inhibits the STING signaling pathway. Anti-inflammatory agent 70 has anti-inflammatory activity.

For research use only. We do not sell to patients.

Anti-inflammatory agent 70 Chemical Structure

Anti-inflammatory agent 70 Chemical Structure

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 736 In-stock
Solution
10 mM * 1 mL in DMSO USD 736 In-stock
Solid
1 mg USD 188 In-stock
5 mg USD 469 In-stock
10 mg USD 751 In-stock
25 mg USD 1502 In-stock
50 mg USD 2403 In-stock
100 mg USD 3846 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Anti-inflammatory agent 70 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Anti-inflammatory agent 70 (N-Me-SP23) is a STING protein degrader and inhibits the STING signaling pathway. Anti-inflammatory agent 70 has anti-inflammatory activity[1].

Molecular Weight

713.69

Formula

C35H35N7O10
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C2=C(NCCCCCCNC(/C=C/C(NC3=CC=C(C=C3)NC(C4=CC=C([N+]([O-])=O)O4)=O)=O)=O)C=CC=C2C(N1C5C(N(C(CC5)=O)C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (140.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4012 mL 7.0058 mL 14.0117 mL
5 mM 0.2802 mL 1.4012 mL 2.8023 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4012 mL 7.0058 mL 14.0117 mL 35.0292 mL
5 mM 0.2802 mL 1.4012 mL 2.8023 mL 7.0058 mL
10 mM 0.1401 mL 0.7006 mL 1.4012 mL 3.5029 mL
15 mM 0.0934 mL 0.4671 mL 0.9341 mL 2.3353 mL
20 mM 0.0701 mL 0.3503 mL 0.7006 mL 1.7515 mL
25 mM 0.0560 mL 0.2802 mL 0.5605 mL 1.4012 mL
30 mM 0.0467 mL 0.2335 mL 0.4671 mL 1.1676 mL
40 mM 0.0350 mL 0.1751 mL 0.3503 mL 0.8757 mL
50 mM 0.0280 mL 0.1401 mL 0.2802 mL 0.7006 mL
60 mM 0.0234 mL 0.1168 mL 0.2335 mL 0.5838 mL
80 mM 0.0175 mL 0.0876 mL 0.1751 mL 0.4379 mL
100 mM 0.0140 mL 0.0701 mL 0.1401 mL 0.3503 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Anti-inflammatory agent 70 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-inflammatory agent 70STINGStimulator of Interferon GenesTMEM173MITAERISMPYSdegradersignaling pathwayinfectionInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Anti-inflammatory agent 70
Cat. No.:
HY-157570
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.