2. Anti-infection
  3. Bacterial
  4. BC-7013

BC-7013 is a novel semi-synthetic pleuromutilin derivative. BC-7013 has excellent activity against Gram-positive pathogenic bacteria. BC-7013 exhibits potent antibacterial properties against both Staphylococcus, Streptococcus and penicillin-resistant Streptococcus pneumoniae. BC-7013 has activity against Gram-positive pathogenic bacteria, BC-7013 is useful in the research of acute bacterial skin and skin structure infection (ABSSSI).

For research use only. We do not sell to patients.

BC-7013 Chemical Structure

BC-7013 Chemical Structure

CAS No. : 1028291-66-8

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Based on 1 publication(s) in Google Scholar

BC-7013 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

BC-7013 is a novel semi-synthetic pleuromutilin derivative. BC-7013 has excellent activity against Gram-positive pathogenic bacteria. BC-7013 exhibits potent antibacterial properties against both Staphylococcus, Streptococcus and penicillin-resistant Streptococcus pneumoniae. BC-7013 has activity against Gram-positive pathogenic bacteria, BC-7013 is useful in the research of acute bacterial skin and skin structure infection (ABSSSI)[1].

IC50 & Target

MIC50: 0.015µg/mL (303 tested S. aureus isolates)[2]
In Vitro

BC-7013 shows strong inhibitory activity against 303 tested S. aureus isolates with a MIC50 value of 0.015 µg/mL[2].
BC-7013 exhibits potent activity against group A streptococci and group B streptococci with MIC90s values of 0.03 µg/mL and 0.06 µg/mL, respectively[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

BC-7013 Related Antibodies
Molecular Weight

500.69

Formula

C29H40O5S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CSC1=CC=CC(CO)=C1)O[C@H]2[C@]3(C)[C@@H](CC[C@]4([C@H]([C@@H]([C@](C=C)(C2)C)O)C)[C@@]3([H])C(CC4)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (199.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9972 mL 9.9862 mL 19.9724 mL
5 mM 0.3994 mL 1.9972 mL 3.9945 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.04%

SDS (252 KB)

COA (256 KB) HNMR (265 KB) RP-HPLC (241 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9972 mL 9.9862 mL 19.9724 mL 49.9311 mL
5 mM 0.3994 mL 1.9972 mL 3.9945 mL 9.9862 mL
10 mM 0.1997 mL 0.9986 mL 1.9972 mL 4.9931 mL
15 mM 0.1331 mL 0.6657 mL 1.3315 mL 3.3287 mL
20 mM 0.0999 mL 0.4993 mL 0.9986 mL 2.4966 mL
25 mM 0.0799 mL 0.3994 mL 0.7989 mL 1.9972 mL
30 mM 0.0666 mL 0.3329 mL 0.6657 mL 1.6644 mL
40 mM 0.0499 mL 0.2497 mL 0.4993 mL 1.2483 mL
50 mM 0.0399 mL 0.1997 mL 0.3994 mL 0.9986 mL
60 mM 0.0333 mL 0.1664 mL 0.3329 mL 0.8322 mL
80 mM 0.0250 mL 0.1248 mL 0.2497 mL 0.6241 mL
100 mM 0.0200 mL 0.0999 mL 0.1997 mL 0.4993 mL
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BC-7013 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BC-70131028291-66-8BC7013BC 7013BacterialinfectionantibiosisStaphylococcusStreptococcusABSSSIInhibitorinhibitorinhibit

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