1. Protein Tyrosine Kinase/RTK
  2. c-Met/HGFR
  3. Canlitinib

Canlitinib is a tyrosine kinase inhibitor, extracted from patent WO2018072614 (IV-2). Canlitinib has the potential for cancer study.

For research use only. We do not sell to patients.

Canlitinib Chemical Structure

Canlitinib Chemical Structure

CAS No. : 2222730-78-9

Size Price Stock Quantity
1 mg USD 130 In-stock
5 mg USD 330 In-stock
10 mg USD 550 In-stock
25 mg USD 1100 In-stock
50 mg USD 1800 In-stock
100 mg USD 2880 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Canlitinib is a tyrosine kinase inhibitor, extracted from patent WO2018072614 (IV-2). Canlitinib has the potential for cancer study.

Molecular Weight

619.61

Formula

C33H31F2N3O7

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(CCCCCOC1=CC2=NC=CC(OC3=CC=C(NC(C4(CC4)C(NC5=CC=C(C=C5)F)=O)=O)C=C3F)=C2C=C1OC)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (161.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6139 mL 8.0696 mL 16.1392 mL
5 mM 0.3228 mL 1.6139 mL 3.2278 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6139 mL 8.0696 mL 16.1392 mL 40.3480 mL
5 mM 0.3228 mL 1.6139 mL 3.2278 mL 8.0696 mL
10 mM 0.1614 mL 0.8070 mL 1.6139 mL 4.0348 mL
15 mM 0.1076 mL 0.5380 mL 1.0759 mL 2.6899 mL
20 mM 0.0807 mL 0.4035 mL 0.8070 mL 2.0174 mL
25 mM 0.0646 mL 0.3228 mL 0.6456 mL 1.6139 mL
30 mM 0.0538 mL 0.2690 mL 0.5380 mL 1.3449 mL
40 mM 0.0403 mL 0.2017 mL 0.4035 mL 1.0087 mL
50 mM 0.0323 mL 0.1614 mL 0.3228 mL 0.8070 mL
60 mM 0.0269 mL 0.1345 mL 0.2690 mL 0.6725 mL
80 mM 0.0202 mL 0.1009 mL 0.2017 mL 0.5043 mL
100 mM 0.0161 mL 0.0807 mL 0.1614 mL 0.4035 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Canlitinib
Cat. No.:
HY-156603
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