2. Anti-infection Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease Cell Cycle/DNA Damage GPCR/G Protein
  3. Bacterial PPAR Prostaglandin Receptor Antibiotic
  4. Cefminox sodium

Cefminox sodium  (Synonyms: MT-141)

Cat. No.: HY-128932 Purity: 99.83%
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Cefminox sodium (MT-141) is a semisynthetic cephamycin, which exhibits a broad spectrum of antibacterial activity. Cefminox sodium (MT-141) also acts as a dual agonist of prostacyclin receptor (IP) and PPARγ, upregulates cAMP production and PTEN expression and inhibits Akt/mTOR signaling. Cefminox sodium (MT-141) also prevents pulmonary arterial hypertension.

For research use only. We do not sell to patients.

Cefminox sodium Chemical Structure

Cefminox sodium Chemical Structure

CAS No. : 75498-96-3

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5 mg USD 30 In-stock
10 mg USD 42 In-stock
25 mg USD 85 In-stock
50 mg USD 140 In-stock
100 mg USD 225 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Cefminox sodium:

Cefminox sodium Related Antibodies

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1 Publications Citing Use of MCE Cefminox sodium

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Description

Cefminox sodium (MT-141) is a semisynthetic cephamycin, which exhibits a broad spectrum of antibacterial activity[1]. Cefminox sodium (MT-141) also acts as a dual agonist of prostacyclin receptor (IP) and PPARγ, upregulates cAMP production and PTEN expression and inhibits Akt/mTOR signaling. Cefminox sodium (MT-141) also prevents pulmonary arterial hypertension[2].

IC50 & Target[1][2]

PPARγ

 

IP Receptor

 

Bacterial

 

Molecular Weight

541.56

Formula

C16H20N7NaO7S3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C(N12)=C(CSC3=NN=NN3C)CS[C@]2([H])[C@](OC)(NC(CSC[C@@H](N)C(O)=O)=O)C1=O)O[Na]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 83.33 mg/mL (153.87 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8465 mL 9.2326 mL 18.4652 mL
5 mM 0.3693 mL 1.8465 mL 3.6930 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 50 mg/mL (92.33 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.8465 mL 9.2326 mL 18.4652 mL 46.1629 mL
5 mM 0.3693 mL 1.8465 mL 3.6930 mL 9.2326 mL
10 mM 0.1847 mL 0.9233 mL 1.8465 mL 4.6163 mL
15 mM 0.1231 mL 0.6155 mL 1.2310 mL 3.0775 mL
20 mM 0.0923 mL 0.4616 mL 0.9233 mL 2.3081 mL
25 mM 0.0739 mL 0.3693 mL 0.7386 mL 1.8465 mL
30 mM 0.0616 mL 0.3078 mL 0.6155 mL 1.5388 mL
40 mM 0.0462 mL 0.2308 mL 0.4616 mL 1.1541 mL
50 mM 0.0369 mL 0.1847 mL 0.3693 mL 0.9233 mL
60 mM 0.0308 mL 0.1539 mL 0.3078 mL 0.7694 mL
80 mM 0.0231 mL 0.1154 mL 0.2308 mL 0.5770 mL
100 mM 0.0185 mL 0.0923 mL 0.1847 mL 0.4616 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Cefminox sodium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cefminox75498-96-3MT-141MT141MT 141BacterialPPARProstaglandin ReceptorAntibioticPeroxisome proliferator-activated receptorsInhibitorinhibitorinhibit

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