2. Others Metabolic Enzyme/Protease Autophagy
  3. Isotope-Labeled Compounds FXR Endogenous Metabolite Autophagy
  4. Chenodeoxycholic acid-d5

Chenodeoxycholic acid-d5  (Synonyms: CDCA-d5)

Cat. No.: HY-76847S3 Purity: ≥98.0%
COA Handling Instructions

Molarity Calculator

Chenodeoxycholic acid-d5 is the deuterium labeled Chenodeoxycholic Acid. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.

For research use only. We do not sell to patients.

Chenodeoxycholic acid-d<sub>5</sub> Chemical Structure

Chenodeoxycholic acid-d5 Chemical Structure

CAS No. : 52840-12-7

Size Price Stock Quantity
1 mg USD 80 In-stock
5 mg USD 210 In-stock
10 mg USD 350 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Chenodeoxycholic acid-d5:

Chenodeoxycholic acid-d5 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Chenodeoxycholic acid-d5 is the deuterium labeled Chenodeoxycholic Acid. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chenodeoxycholic acid-d5 Related Antibodies
Molecular Weight

397.60

Formula

C24H35D5O4
CAS No.
Unlabeled CAS

474-25-9
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](C([2H])([2H])[C@](C([2H])([2H])C4)([2H])O)([H])C[C@H]3O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (125.75 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5151 mL 12.5755 mL 25.1509 mL
5 mM 0.5030 mL 2.5151 mL 5.0302 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5151 mL 12.5755 mL 25.1509 mL 62.8773 mL
5 mM 0.5030 mL 2.5151 mL 5.0302 mL 12.5755 mL
10 mM 0.2515 mL 1.2575 mL 2.5151 mL 6.2877 mL
15 mM 0.1677 mL 0.8384 mL 1.6767 mL 4.1918 mL
20 mM 0.1258 mL 0.6288 mL 1.2575 mL 3.1439 mL
25 mM 0.1006 mL 0.5030 mL 1.0060 mL 2.5151 mL
30 mM 0.0838 mL 0.4192 mL 0.8384 mL 2.0959 mL
40 mM 0.0629 mL 0.3144 mL 0.6288 mL 1.5719 mL
50 mM 0.0503 mL 0.2515 mL 0.5030 mL 1.2575 mL
60 mM 0.0419 mL 0.2096 mL 0.4192 mL 1.0480 mL
80 mM 0.0314 mL 0.1572 mL 0.3144 mL 0.7860 mL
100 mM 0.0252 mL 0.1258 mL 0.2515 mL 0.6288 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Chenodeoxycholic acid-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chenodeoxycholic acid-d552840-12-7CDCA-d5Isotope-Labeled CompoundsFXREndogenous MetaboliteAutophagyNR1H4Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Chenodeoxycholic acid-d5
Cat. No.:
HY-76847S3
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.