Cholesteryl arachidonate

Name: Cholesteryl arachidonate
Brand: MedChemExpress
SKU: HY-113369
Rating: 4.5 (1 reviews)

Cat. No.: HY-113369 Purity: 99.20%: Data Sheet
SDS

COA
Handling Instructions Technical Support

Solubility

In Vivo Dissolution Calculator

Cholesteryl arachidonate is an endogenous metabolite.

For research use only. We do not sell to patients.

Cholesteryl arachidonate Chemical Structure

CAS No. : 604-34-2

Size	Price	Stock	Quantity
1 mg	USD 55	In-stock	Estimated Time of Arrival: April 14
5 mg	USD 135	In-stock	Estimated Time of Arrival: April 14
10 mg		Get quote
50 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Cholesteryl arachidonate:

Cholesteryl arachidonate-d₈ Get quote

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Description

Cholesteryl arachidonate is an endogenous metabolite.

IC₅₀ & Target

Human Endogenous Metabolite

Molecular Weight

673.11

Formula

C₄₇H₇₆O₂

CAS No.

604-34-2

Appearance

Oil

Color

Colorless to light yellow

SMILES

CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

Structure Classification

Steroids

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (148.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.4856 mL	7.4282 mL	14.8564 mL
5 mM	0.2971 mL	1.4856 mL	2.9713 mL
10 mM	0.1486 mL	0.7428 mL	1.4856 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (3.71 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (3.71 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, PEG300/PEG400, Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Purity & Documentation

Purity: 99.20%

Select Batch:

Data Sheet (237 KB) SDS (252 KB)

COA (240 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.4856 mL	7.4282 mL	14.8564 mL	37.1410 mL
	5 mM	0.2971 mL	1.4856 mL	2.9713 mL	7.4282 mL
	10 mM	0.1486 mL	0.7428 mL	1.4856 mL	3.7141 mL
	15 mM	0.0990 mL	0.4952 mL	0.9904 mL	2.4761 mL
	20 mM	0.0743 mL	0.3714 mL	0.7428 mL	1.8571 mL
	25 mM	0.0594 mL	0.2971 mL	0.5943 mL	1.4856 mL
	30 mM	0.0495 mL	0.2476 mL	0.4952 mL	1.2380 mL
	40 mM	0.0371 mL	0.1857 mL	0.3714 mL	0.9285 mL
	50 mM	0.0297 mL	0.1486 mL	0.2971 mL	0.7428 mL
	60 mM	0.0248 mL	0.1238 mL	0.2476 mL	0.6190 mL
	80 mM	0.0186 mL	0.0929 mL	0.1857 mL	0.4643 mL
	100 mM	0.0149 mL	0.0743 mL	0.1486 mL	0.3714 mL