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cis-Indatraline hydrochloride  (Synonyms: cis-Lu 19-005)

Cat. No.: HY-110019A Purity: 99.64%
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cis-Indatraline (cis-Lu 19-005) hydrochloride is an active compound. cis-Indatraline (cis-Lu 19-005) hydrochloride can be used for the research of neurodegenerative diseases.

For research use only. We do not sell to patients.

cis-Indatraline hydrochloride Chemical Structure

cis-Indatraline hydrochloride Chemical Structure

CAS No. : 86939-08-4

Size Price Stock Quantity
5 mg USD 264 In-stock
10 mg USD 422 In-stock
25 mg USD 840 In-stock
50 mg USD 1345 In-stock
100 mg USD 1980 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of cis-Indatraline hydrochloride:

cis-Indatraline hydrochloride Related Antibodies

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Description

cis-Indatraline (cis-Lu 19-005) hydrochloride is an active compound. cis-Indatraline (cis-Lu 19-005) hydrochloride can be used for the research of neurodegenerative diseases[1].

Molecular Weight

328.66

Formula

C16H16Cl3N
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CN[C@@H]1C[C@H](C2=CC=C(Cl)C(Cl)=C2)C3=C1C=CC=C3.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (152.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0427 mL 15.2133 mL 30.4266 mL
5 mM 0.6085 mL 3.0427 mL 6.0853 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 5 mg/mL (15.21 mM); Clear solution

    This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 5 mg/mL (15.21 mM); Clear solution

    This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0427 mL 15.2133 mL 30.4266 mL 76.0665 mL
5 mM 0.6085 mL 3.0427 mL 6.0853 mL 15.2133 mL
10 mM 0.3043 mL 1.5213 mL 3.0427 mL 7.6066 mL
15 mM 0.2028 mL 1.0142 mL 2.0284 mL 5.0711 mL
20 mM 0.1521 mL 0.7607 mL 1.5213 mL 3.8033 mL
25 mM 0.1217 mL 0.6085 mL 1.2171 mL 3.0427 mL
30 mM 0.1014 mL 0.5071 mL 1.0142 mL 2.5355 mL
40 mM 0.0761 mL 0.3803 mL 0.7607 mL 1.9017 mL
50 mM 0.0609 mL 0.3043 mL 0.6085 mL 1.5213 mL
60 mM 0.0507 mL 0.2536 mL 0.5071 mL 1.2678 mL
80 mM 0.0380 mL 0.1902 mL 0.3803 mL 0.9508 mL
100 mM 0.0304 mL 0.1521 mL 0.3043 mL 0.7607 mL
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cis-Indatraline hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

cis-Indatraline86939-08-4cis-Lu 19-005Othersactive compoundneurodegenerative diseasesInhibitorinhibitorinhibit

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