2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. CP-775146

CP-775146 is a selective PPARα agonist that binds strongly to the PPARα ligand. CP-775146 efficiently alleviates obesity-induced liver damage, prevents lipid accumulation by activating the liver fatty acid β-oxidation pathway.

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CP-775146 Chemical Structure

CP-775146 Chemical Structure

CAS No. : 702680-17-9

Size Price Stock Quantity
1 mg USD 144 In-stock
5 mg USD 360 In-stock
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Based on 1 publication(s) in Google Scholar

CP-775146 Related Antibodies

Top Publications Citing Use of Products

View All PPAR Isoform Specific Products:

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PPARα PPARβ/δ PPARγ PPAR PPARδ

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Description

CP-775146 is a selective PPARα agonist that binds strongly to the PPARα ligand. CP-775146 efficiently alleviates obesity-induced liver damage, prevents lipid accumulation by activating the liver fatty acid β-oxidation pathway[1].

Molecular Weight

423.54

Formula

C26H33NO4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(OC1=CC=CC([C@H]2CN(C(CC3=CC=C(C(C)C)C=C3)=O)CCC2)=C1)(C)C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 42 mg/mL (99.16 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3611 mL 11.8053 mL 23.6105 mL
5 mM 0.4722 mL 2.3611 mL 4.7221 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3611 mL 11.8053 mL 23.6105 mL 59.0263 mL
5 mM 0.4722 mL 2.3611 mL 4.7221 mL 11.8053 mL
10 mM 0.2361 mL 1.1805 mL 2.3611 mL 5.9026 mL
15 mM 0.1574 mL 0.7870 mL 1.5740 mL 3.9351 mL
20 mM 0.1181 mL 0.5903 mL 1.1805 mL 2.9513 mL
25 mM 0.0944 mL 0.4722 mL 0.9444 mL 2.3611 mL
30 mM 0.0787 mL 0.3935 mL 0.7870 mL 1.9675 mL
40 mM 0.0590 mL 0.2951 mL 0.5903 mL 1.4757 mL
50 mM 0.0472 mL 0.2361 mL 0.4722 mL 1.1805 mL
60 mM 0.0394 mL 0.1968 mL 0.3935 mL 0.9838 mL
80 mM 0.0295 mL 0.1476 mL 0.2951 mL 0.7378 mL
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CP-775146 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CP-775146702680-17-9CP775146CP 775146PPARPeroxisome proliferator-activated receptorsPPARα agonistobesity-induced liver damageprevents lipid accumulationliver fatty acidβ-oxidation pathwayInhibitorinhibitorinhibit

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