2. Others Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Endogenous Metabolite
  4. D-Alanine-d3

D-Alanine-d3  (Synonyms: (R)-Alanine-d3; Ba 2776-d3; D-α-Alanine-d3)

Cat. No.: HY-41700S Purity: 99.31%
SDS COA Handling Instructions

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D-Alanine-d3 is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

For research use only. We do not sell to patients.

D-Alanine-d<sub>3</sub> Chemical Structure

D-Alanine-d3 Chemical Structure

CAS No. : 177614-69-6

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10 mg USD 120 In-stock
25 mg USD 240 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of D-Alanine-d3:

D-Alanine-d3 Related Antibodies

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Description

D-Alanine-d3 is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

D-Alanine-d3 Related Antibodies
Molecular Weight

92.11

Formula

C3H4D3NO2
CAS No.
Unlabeled CAS

338-69-2
Appearance

Solid

Color

White to off-white

SMILES

OC([C@H](N)C([2H])([2H])[2H])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (1085.66 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 10.8566 mL 54.2829 mL 108.5658 mL
5 mM 2.1713 mL 10.8566 mL 21.7132 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.31%

SDS (393 KB)

COA (249 KB) HNMR (2804 KB) RP-HPLC (780 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 10.8566 mL 54.2829 mL 108.5658 mL 271.4146 mL
5 mM 2.1713 mL 10.8566 mL 21.7132 mL 54.2829 mL
10 mM 1.0857 mL 5.4283 mL 10.8566 mL 27.1415 mL
15 mM 0.7238 mL 3.6189 mL 7.2377 mL 18.0943 mL
20 mM 0.5428 mL 2.7141 mL 5.4283 mL 13.5707 mL
25 mM 0.4343 mL 2.1713 mL 4.3426 mL 10.8566 mL
30 mM 0.3619 mL 1.8094 mL 3.6189 mL 9.0472 mL
40 mM 0.2714 mL 1.3571 mL 2.7141 mL 6.7854 mL
50 mM 0.2171 mL 1.0857 mL 2.1713 mL 5.4283 mL
60 mM 0.1809 mL 0.9047 mL 1.8094 mL 4.5236 mL
80 mM 0.1357 mL 0.6785 mL 1.3571 mL 3.3927 mL
100 mM 0.1086 mL 0.5428 mL 1.0857 mL 2.7141 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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D-Alanine-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D-Alanine-d3177614-69-6(R)-Alanine-d3Ba 2776-d3D-α-Alanine-d3Isotope-Labeled CompoundsEndogenous MetaboliteInhibitorinhibitorinhibit

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