2. Protein Tyrosine Kinase/RTK
  3. Btk
  4. DD-03-171

DD-03-171 is a BTK, IKFZ1 and IKFZ3 degrader, the BTK IC50 a value of 5.1 nM. DD-03-171 has an antiproliferative effect on mantle cell lymphoma (MCL) cells.

For research use only. We do not sell to patients.

DD-03-171 Chemical Structure

DD-03-171 Chemical Structure

CAS No. : 2366132-45-6

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Based on 1 publication(s) in Google Scholar

DD-03-171 Related Antibodies

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Description

DD-03-171 is a BTK, IKFZ1 and IKFZ3 degrader, the BTK IC50 a value of 5.1 nM. DD-03-171 has an antiproliferative effect on mantle cell lymphoma (MCL) cells[1].

IC50 & Target

IKFC[1]
Molecular Weight

991.14

Formula

C55H62N10O8
CAS No.
SMILES

O=C(NC1=CC=CC(C(N=C2NC3=CC=C(C(N4CCN(CCCCCCNC(CNC5=CC=CC(C(N6C(CC7)C(NC7=O)=O)=O)=C5C6=O)=O)CC4)=O)C=C3)=CN(C)C2=O)=C1C)C8=CC=C(C(C)(C)C)C=C8
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DD-03-171 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DD-03-1712366132-45-6BtkBruton tyrosine kinaseBTKIKFZ1IKFZ3MCLInhibitorinhibitorinhibit

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HY-122830
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