2. Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  3. ADC Cytotoxin Topoisomerase
  4. Decyclohexanamine-Exatecan

Decyclohexanamine-Exatecan is a Camptothecin derivative, compound a, extracted from patent WO2020219287 A1.

For research use only. We do not sell to patients.

Decyclohexanamine-Exatecan Chemical Structure

Decyclohexanamine-Exatecan Chemical Structure

CAS No. : 2505045-51-0

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 462 In-stock
Solution
10 mM * 1 mL in DMSO USD 462 In-stock
Solid
5 mg USD 420 In-stock
10 mg USD 629 In-stock
25 mg USD 1258 In-stock
50 mg USD 1888 In-stock
100 mg USD 2832 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Decyclohexanamine-Exatecan Related Antibodies

Top Publications Citing Use of Products

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  • Biological Activity

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Description

Decyclohexanamine-Exatecan is a Camptothecin derivative, compound a, extracted from patent WO2020219287 A1.

IC50 & Target

Camptothecins

 

Molecular Weight

380.37

Formula

C21H17FN2O4
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC[C@@]1(C2=C(COC1=O)C(N3C(C(C(C3)=CC4=C5)=NC4=CC(F)=C5C)=C2)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 32 mg/mL (84.13 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6290 mL 13.1451 mL 26.2902 mL
5 mM 0.5258 mL 2.6290 mL 5.2580 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6290 mL 13.1451 mL 26.2902 mL 65.7255 mL
5 mM 0.5258 mL 2.6290 mL 5.2580 mL 13.1451 mL
10 mM 0.2629 mL 1.3145 mL 2.6290 mL 6.5725 mL
15 mM 0.1753 mL 0.8763 mL 1.7527 mL 4.3817 mL
20 mM 0.1315 mL 0.6573 mL 1.3145 mL 3.2863 mL
25 mM 0.1052 mL 0.5258 mL 1.0516 mL 2.6290 mL
30 mM 0.0876 mL 0.4382 mL 0.8763 mL 2.1908 mL
40 mM 0.0657 mL 0.3286 mL 0.6573 mL 1.6431 mL
50 mM 0.0526 mL 0.2629 mL 0.5258 mL 1.3145 mL
60 mM 0.0438 mL 0.2191 mL 0.4382 mL 1.0954 mL
80 mM 0.0329 mL 0.1643 mL 0.3286 mL 0.8216 mL
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Decyclohexanamine-Exatecan Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Decyclohexanamine-Exatecan2505045-51-0ADC CytotoxinTopoisomeraseADC PayloadCamptothecin DerivativeInhibitorinhibitorinhibit

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