2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. F-SAHA

F-SAHA  (Synonyms: p-Fluoro-SAHA)

Cat. No.: HY-159045 Purity: 99.90%
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F-SAHA is a HDAC inhibitor (HDACi) and its 18F labeled derivative can be used in tumor imaging research.

For research use only. We do not sell to patients.

F-SAHA Chemical Structure

F-SAHA Chemical Structure

CAS No. : 149648-08-8

Size Price Stock Quantity
5 mg USD 55 In-stock
10 mg USD 88 In-stock
25 mg USD 176 In-stock
50 mg USD 280 In-stock
100 mg USD 450 In-stock
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Based on 1 publication(s) in Google Scholar

F-SAHA Related Antibodies

Top Publications Citing Use of Products

View All HDAC Isoform Specific Products:

View All Isoforms
HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

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Description

F-SAHA is a HDAC inhibitor (HDACi) and its 18F labeled derivative can be used in tumor imaging research[1].

Molecular Weight

282.31

Formula

C14H19FN2O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CCCCCCC(NC1=CC=C(C=C1)F)=O)NO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 116.67 mg/mL (413.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5422 mL 17.7110 mL 35.4221 mL
5 mM 0.7084 mL 3.5422 mL 7.0844 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5422 mL 17.7110 mL 35.4221 mL 88.5551 mL
5 mM 0.7084 mL 3.5422 mL 7.0844 mL 17.7110 mL
10 mM 0.3542 mL 1.7711 mL 3.5422 mL 8.8555 mL
15 mM 0.2361 mL 1.1807 mL 2.3615 mL 5.9037 mL
20 mM 0.1771 mL 0.8856 mL 1.7711 mL 4.4278 mL
25 mM 0.1417 mL 0.7084 mL 1.4169 mL 3.5422 mL
30 mM 0.1181 mL 0.5904 mL 1.1807 mL 2.9518 mL
40 mM 0.0886 mL 0.4428 mL 0.8856 mL 2.2139 mL
50 mM 0.0708 mL 0.3542 mL 0.7084 mL 1.7711 mL
60 mM 0.0590 mL 0.2952 mL 0.5904 mL 1.4759 mL
80 mM 0.0443 mL 0.2214 mL 0.4428 mL 1.1069 mL
100 mM 0.0354 mL 0.1771 mL 0.3542 mL 0.8856 mL
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F-SAHA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

F-SAHA149648-08-8p-Fluoro-SAHAHDACHistone deacetylasesHDACitumor imagingInhibitorinhibitorinhibit

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