2. Immunology/Inflammation Apoptosis
  3. COX Apoptosis
  4. Flurbiprofen-d3

Flurbiprofen-d3  (Synonyms: dl-Flurbiprofen-d3)

Cat. No.: HY-10582S Purity: 99.94%
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Flurbiprofen-d3 is the deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer[1][2][3].

For research use only. We do not sell to patients.

Flurbiprofen-d<sub>3</sub> Chemical Structure

Flurbiprofen-d3 Chemical Structure

CAS No. : 1185133-81-6

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1 mg USD 110 In-stock
5 mg USD 320 In-stock
10 mg USD 520 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Flurbiprofen-d3:

Flurbiprofen-d3 Related Antibodies

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Description

Flurbiprofen-d3 is the deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Flurbiprofen-d3 Related Antibodies
Molecular Weight

247.28

Formula

C15H10D3FO2
CAS No.
Unlabeled CAS

5104-49-4
Appearance

Solid

Color

White to off-white

SMILES

FC1=CC(C(C(O)=O)C([2H])([2H])[2H])=CC=C1C2=CC=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (404.40 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 100 mg/mL (404.40 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0440 mL 20.2200 mL 40.4400 mL
5 mM 0.8088 mL 4.0440 mL 8.0880 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 4.0440 mL 20.2200 mL 40.4400 mL 101.1000 mL
5 mM 0.8088 mL 4.0440 mL 8.0880 mL 20.2200 mL
10 mM 0.4044 mL 2.0220 mL 4.0440 mL 10.1100 mL
15 mM 0.2696 mL 1.3480 mL 2.6960 mL 6.7400 mL
20 mM 0.2022 mL 1.0110 mL 2.0220 mL 5.0550 mL
25 mM 0.1618 mL 0.8088 mL 1.6176 mL 4.0440 mL
30 mM 0.1348 mL 0.6740 mL 1.3480 mL 3.3700 mL
40 mM 0.1011 mL 0.5055 mL 1.0110 mL 2.5275 mL
50 mM 0.0809 mL 0.4044 mL 0.8088 mL 2.0220 mL
60 mM 0.0674 mL 0.3370 mL 0.6740 mL 1.6850 mL
80 mM 0.0505 mL 0.2527 mL 0.5055 mL 1.2637 mL
100 mM 0.0404 mL 0.2022 mL 0.4044 mL 1.0110 mL
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Flurbiprofen-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Flurbiprofen-d31185133-81-6dl-Flurbiprofen-d3COXApoptosisCyclooxygenaseInhibitorinhibitorinhibit

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