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  4. Fmoc-7-amino-heptanoic acid

Fmoc-7-amino-heptanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. Fmoc-7-amino-heptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

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Fmoc-7-amino-heptanoic acid Chemical Structure

Fmoc-7-amino-heptanoic acid Chemical Structure

CAS No. : 127582-76-7

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Fmoc-7-amino-heptanoic acid Related Antibodies

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Description

Fmoc-7-amino-heptanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. Fmoc-7-amino-heptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Molecular Weight

367.44

Formula

C22H25NO4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CCCCCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Purity & Documentation
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Fmoc-7-amino-heptanoic acid Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • What are the differences between HY-50767, HY-50767A, HY-50767B, HY-50767C, HY-50767D, and HY-A0065?

    The biological activities of HY-50767, HY-50767A, HY-50767B, HY-50767C, HY-50767D, and HY-A0065 are equivalent. HY-50767 is in the free base, and the others are in salt form, so the solubility will be different.

Keywords:

Fmoc-7-amino-heptanoic acid127582-76-7PROTAC LinkersInhibitorinhibitorinhibit

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