2. GPCR/G Protein
  3. Adenylate Cyclase
  4. PACAP (6-27) (human, ovine, rat)

PACAP (6-27) (human, ovine, rat)  (Synonyms: Pituitary adenylate cyclase-activating peptide (6-27))

Cat. No.: HY-P3117 Purity: 98.89%
SDS COA Handling Instructions Technical Support

PACAP (6-27) (human, ovine, rat) is a PACAP receptor antagonist that blocks the canine adrenal catecholamine response to exogenous vasoactive intestinal peptide (VIP). PACAP (6-27) (human, ovine, rat) has the potential to study cardiovascular and neurological diseases.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

PACAP (6-27) (human, ovine, rat) Chemical Structure

PACAP (6-27) (human, ovine, rat) Chemical Structure

CAS No. : 136134-68-4

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Based on 1 publication(s) in Google Scholar

PACAP (6-27) (human, ovine, rat) Related Antibodies

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Description

PACAP (6-27) (human, ovine, rat) is a PACAP receptor antagonist that blocks the canine adrenal catecholamine response to exogenous vasoactive intestinal peptide (VIP). PACAP (6-27) (human, ovine, rat) has the potential to study cardiovascular and neurological diseases[1].

IC50 & Target

PACAP receptor[1].
Molecular Weight

2638.09

Formula

C121H193N33O31S
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2
Sequence Shortening

FTDSYSRYRKQMAVKKYLAAVL-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (37.91 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.3791 mL 1.8953 mL 3.7906 mL
5 mM 0.0758 mL 0.3791 mL 0.7581 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.3791 mL 1.8953 mL 3.7906 mL 9.4766 mL
5 mM 0.0758 mL 0.3791 mL 0.7581 mL 1.8953 mL
10 mM 0.0379 mL 0.1895 mL 0.3791 mL 0.9477 mL
15 mM 0.0253 mL 0.1264 mL 0.2527 mL 0.6318 mL
20 mM 0.0190 mL 0.0948 mL 0.1895 mL 0.4738 mL
25 mM 0.0152 mL 0.0758 mL 0.1516 mL 0.3791 mL
30 mM 0.0126 mL 0.0632 mL 0.1264 mL 0.3159 mL
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PACAP (6-27) (human, ovine, rat) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PACAP (6-27) (human, ovine, rat)136134-68-4Pituitary adenylate cyclase-activating peptide (6-27)Adenylate CyclaseAdenylyl cyclaseInhibitorinhibitorinhibit

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