2. Metabolic Enzyme/Protease Cell Cycle/DNA Damage
  3. Endogenous Metabolite DNA/RNA Synthesis
  4. Folic acid disodium

Folic acid disodium  (Synonyms: Vitamin B9 disodium; Vitamin M disodium)

Cat. No.: HY-16637D Purity: 99.15%
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Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·105 g/s. Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia.

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Folic acid disodium Chemical Structure

Folic acid disodium Chemical Structure

CAS No. : 29704-76-5

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Based on 8 publication(s) in Google Scholar

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Folic acid disodium Related Antibodies

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Description

Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·105 g/s[1]. Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia[2].

Molecular Weight

485.36

Formula

C19H17N7Na2O6
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(O[Na])CC[C@@H](C(O[Na])=O)NC(C1=CC=C(NCC2=CN=C3N=C(N)NC(C3=N2)=O)C=C1)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (206.03 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0603 mL 10.3016 mL 20.6033 mL
5 mM 0.4121 mL 2.0603 mL 4.1207 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.0603 mL 10.3016 mL 20.6033 mL 51.5082 mL
5 mM 0.4121 mL 2.0603 mL 4.1207 mL 10.3016 mL
10 mM 0.2060 mL 1.0302 mL 2.0603 mL 5.1508 mL
15 mM 0.1374 mL 0.6868 mL 1.3736 mL 3.4339 mL
20 mM 0.1030 mL 0.5151 mL 1.0302 mL 2.5754 mL
25 mM 0.0824 mL 0.4121 mL 0.8241 mL 2.0603 mL
30 mM 0.0687 mL 0.3434 mL 0.6868 mL 1.7169 mL
40 mM 0.0515 mL 0.2575 mL 0.5151 mL 1.2877 mL
50 mM 0.0412 mL 0.2060 mL 0.4121 mL 1.0302 mL
60 mM 0.0343 mL 0.1717 mL 0.3434 mL 0.8585 mL
80 mM 0.0258 mL 0.1288 mL 0.2575 mL 0.6439 mL
100 mM 0.0206 mL 0.1030 mL 0.2060 mL 0.5151 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Folic acid disodium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Folic acid disodium29704-76-5Vitamin B9 disodiumVitamin M disodiumEndogenous MetaboliteDNA/RNA Synthesisneural tube defectsischemicprecancerous altered cellsmegaloblastic anemiaInhibitorinhibitorinhibit

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