2. Gene
  3. NUBP2 - NUBP iron-sulfur cluster assembly factor 2, cytosolic Gene

NUBP2 - NUBP iron-sulfur cluster assembly factor 2, cytosolic Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CFD1; CIAO6; NBP 2; NUBP1

Gene ID: 10101 | Gene type: protein coding

About NUBP2

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:1,782,960-1,789,186 (from NCBI)

This gene has 16 transcripts (splice variants), 190 orthologues and 2 paralogues. Ubiquitous expression in fat (RPKM 8.3), prostate (RPKM 7.4) and 25 other tissues.

Summary

This gene encodes an adenosine triphosphate (ATP) and metal-binding protein that is required for the assembly of cyotosolic iron-sulfur proteins. The encoded protein functions in a heterotetramer with nucleotide-binding protein 1 (NUBP1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]

NUBP2 Products(3)

mRNA Protein Name
NM_001284501.2 NP_001271430.1 cytosolic Fe-S cluster assembly factor NUBP2 isoform 2
NM_001284502.2 NP_001271431.1 cytosolic Fe-S cluster assembly factor NUBP2 isoform 3
NM_012225.4 NP_036357.1 cytosolic Fe-S cluster assembly factor NUBP2 isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18573874 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NUBP2 Protein Structure

AAA_31

AAA_31: AAA domain (16 - 67)

ParA

ParA: NUBPL iron-transfer P-loop NTPase (126 - 208)

  • 0
  • 100
  • 200
  • 271 a.a.
Protein Preferred Names Protein Names

cytosolic Fe-S cluster assembly factor NUBP2

homolog of yeast cytosolic Fe-S cluster deficient 1

Related Diseases

Diseases Alias
Spinocerebellar Ataxia 38

Spinocerebellar Ataxia Type 38

SCA38

Ataxia, Spinocerebellar, Type 38
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09652 NUBP2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus NUBP2 VGNC VGNC:68585
Bos taurus NUBP2 VGNC VGNC:32316
Macaca mulatta NUBP2 VGNC VGNC:75547
Mus musculus NUBP2 MGD MGI:1347072
Canis familiaris NUBP2 VGNC VGNC:44018
Rattus norvegicus NUBP2 RGD RGD:1305113