MDFI - MyoD family inhibitor Gene

Homo sapiens

Also known as I-MF; I-mfa

Gene ID: 4188 | Gene type: protein coding

About MDFI

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:41,637,018-41,654,244 (from NCBI)

This gene has 9 transcripts (splice variants), 192 orthologues and 2 paralogues. Biased expression in fat (RPKM 11.0), placenta (RPKM 3.0) and 12 other tissues.

Summary

This protein is a transcription factor that negatively regulates Other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. [provided by RefSeq, Jul 2008]

MDFI Products(4)

mRNA	Protein	Name
NM_001300804.2	NP_001287733.1	myoD family inhibitor isoform 1
NM_001300805.2	NP_001287734.1	myoD family inhibitor isoform 2
NM_001300806.2	NP_001287735.1	myoD family inhibitor isoform 1
NM_005586.4	NP_005577.1	myoD family inhibitor isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MDFI Protein Structure

MDFI

0
100
200
246 a.a.

Protein Preferred Names

Protein Names

myoD family inhibitor

inhibitor of MyoD family a

MDFI Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	MDFI	Q99750	NR1H2	Homo sapiens	F1D8P7	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	NR1H2	Homo sapiens	F1D8P7	Y2H Array	25416956
Intra	MDFI	Q99750	CREB5	Homo sapiens	Q02930-3	Validated Y2H	27107012
Intra	MDFI	Q99750	CREB5	Homo sapiens	Q02930-3	BFG-2H	27107012
Intra	MDFI	Q99750	CREB5	Homo sapiens	Q02930-3	Y2H Array	25416956
Intra	MDFI	Q99750	CREB5	Homo sapiens	Q02930-3	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	MXI1	Homo sapiens	P50539-3	Validated Y2H	32296183
Intra	MDFI	Q99750	ZNF138	Homo sapiens	P52744-2	Validated Y2H	25416956
Intra	MDFI	Q99750	ZNF138	Homo sapiens	P52744-2	Y2H Array	25416956
Intra	MDFI	Q99750	RTP5	Homo sapiens	Q14D33	Validated Y2H	25416956
Intra	MDFI	Q99750	RTP5	Homo sapiens	Q14D33	Y2H Array	25416956
Intra	MDFI	Q99750	RTP5	Homo sapiens	Q14D33	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	GNG5	Homo sapiens	P63218	Validated Y2H	25416956
Intra	MDFI	Q99750	GNG5	Homo sapiens	P63218	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	GNG5	Homo sapiens	P63218	Y2H Array	25416956
Intra	MDFI	Q99750	ADAMTSL3	Homo sapiens	P82987	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	AKAP17A	Homo sapiens	Q02040-3	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	REG3A	Homo sapiens	Q06141	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	OLIG3	Homo sapiens	Q7RTU3	Y2H Array	25416956
Intra	MDFI	Q99750	OLIG3	Homo sapiens	Q7RTU3	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	ZNF844	Homo sapiens	Q08AG5	Y2H Array	25416956
Intra	MDFI	Q99750	ZNF844	Homo sapiens	Q08AG5	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	RIPPLY1	Homo sapiens	Q0D2K3	Validated Y2H	25416956
Intra	MDFI	Q99750	RIPPLY1	Homo sapiens	Q0D2K3	Y2H Array	25416956
Intra	MDFI	Q99750	FAAP100	Homo sapiens	Q0VG06-3	Validated Y2H	25416956
Intra	MDFI	Q99750	FAAP100	Homo sapiens	Q0VG06-3	Y2H Array	25416956
Intra	MDFI	Q99750	ZNF155	Homo sapiens	Q12901-2	Validated Y2H	25416956
Intra	MDFI	Q99750	ZNF155	Homo sapiens	Q12901-2	Y2H Array	25416956
Intra	MDFI	Q99750	EIF4A2	Homo sapiens	Q14240-2	Validated Y2H	25416956
Intra	MDFI	Q99750	EIF4A2	Homo sapiens	Q14240-2	Y2H Array	25416956
Intra	MDFI	Q99750	PIH1D2	Homo sapiens	Q8WWB5	Validated Y2H	25416956
Intra	MDFI	Q99750	PIH1D2	Homo sapiens	Q8WWB5	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	PIH1D2	Homo sapiens	Q8WWB5	Y2H Array	25416956
Intra	MDFI	Q99750	ZNF79	Homo sapiens	Q15937	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	ZNF79	Homo sapiens	Q15937	Validated Y2H	25416956
Intra	MDFI	Q99750	ZNF79	Homo sapiens	Q15937	Y2H Array	25416956
Intra	MDFI	Q99750	CCDC198	Homo sapiens	Q9NVL8	Validated Y2H	25416956
Intra	MDFI	Q99750	CCDC198	Homo sapiens	Q9NVL8	Y2H Array	25416956
Intra	MDFI	Q99750	ZNF578	Homo sapiens	Q3MI94	Validated Y2H	25416956
Intra	MDFI	Q99750	ZNF578	Homo sapiens	Q3MI94	Y2H Array	25416956
Intra	MDFI	Q99750	TNP2	Homo sapiens	Q4VB56	Y2H Array	25416956
Intra	MDFI	Q99750	TNP2	Homo sapiens	Q4VB56	Validated Y2H	25416956
Intra	MDFI	Q99750	CC2D1B	Homo sapiens	Q5T0F9	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	CC2D1B	Homo sapiens	Q5T0F9	Y2H Array	25416956
Intra	MDFI	Q99750	LCE3E	Homo sapiens	Q5T5B0	Y2H Array	25416956
Intra	MDFI	Q99750	LCE1B	Homo sapiens	Q5T7P3	Y2H Array	29892012
Intra	MDFI	Q99750	LCE4A	Homo sapiens	Q5TA78	Validated Y2H	25416956
Intra	MDFI	Q99750	yt011_human	Homo sapiens	Q5W150	Validated Y2H	25416956
Intra	MDFI	Q99750	yt011_human	Homo sapiens	Q5W150	Y2H Array	25416956
Intra	MDFI	Q99750	yt011_human	Homo sapiens	Q5W150	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	u633c_human	Homo sapiens	Q5XG85	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	u633c_human	Homo sapiens	Q5XG85	Validated Y2H	25416956
Intra	MDFI	Q99750	PID1	Homo sapiens	Q7Z2X4	Validated Y2H	25416956
Intra	MDFI	Q99750	PID1	Homo sapiens	Q7Z2X4	Y2H Array	25416956
Intra	MDFI	Q99750	LIMS2	Homo sapiens	Q7Z4I7-5	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	ZNF433	Homo sapiens	Q8N7K0	Validated Y2H	25416956
Intra	MDFI	Q99750	ZNF461	Homo sapiens	Q8TAF7	Y2H Prey Pooling	32296183
Intra	MDFI	Q99750	ZNF564	Homo sapiens	Q8TBZ8	Y2H Array	25416956
Intra	MDFI	Q99750	DCANP1	Homo sapiens	Q8TF63	Y2H Array	31515488
Intra	MDFI	Q99750	DCANP1	Homo sapiens	Q8TF63	Y2H Array	25416956
Intra	MDFI	Q99750	CTRC	Homo sapiens	Q99895	Validated Y2H	32296183
Intra	MDFI	Q99750	SHFL	Homo sapiens	Q9NUL5	Y2H Array	25416956
Intra	MDFI	Q99750	SHFL	Homo sapiens	Q9NUL5	Validated Y2H	25416956
Intra	MDFI	Q99750	POLL	Homo sapiens	Q9UGP5-2	Validated Y2H	32296183
Intra	MDFI	Q99750	ZNF223	Homo sapiens	Q9UK11	Y2H Array	25416956
Intra	MDFI	Q99750	ZNF223	Homo sapiens	Q9UK11	Validated Y2H	25416956
Intra	MDFI	Q99750	ZNF223	Homo sapiens	Q9UK11	Validated Y2H	32296183
Intra	MDFI	Q99750	ZNF223	Homo sapiens	Q9UK11	Y2H Array	31515488
Intra	MDFI	Q99750	GTF3C5	Homo sapiens	Q9Y5Q8	Y2H Array	25416956
Intra	MDFI	Q99750	NUBP2	Homo sapiens	Q9Y5Y2	Validated Y2H	32296183
Intra	MDFI	Q99750	TUSC2	Homo sapiens	O75896	Y2H Array	29892012
Intra	MDFI	Q99750	TUSC2	Homo sapiens	O75896	Y2H Array	25416956
Intra	MDFI	Q99750	PRKAB2	Homo sapiens	O43741	Validated Y2H	27107012
Intra	MDFI	Q99750	PRKAB2	Homo sapiens	O43741	Y2H Array	31515488
Intra	MDFI	Q99750	PRKAB2	Homo sapiens	O43741	Validated Y2H	25416956
Intra	MDFI	Q99750	HTR1B	Homo sapiens	P28222	Validated Y2H	25416956
Intra	MDFI	Q99750	HTR1B	Homo sapiens	P28222	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	PATZ1	Homo sapiens	Q9HBE1-4	Validated Y2H	32296183
Intra	MDFI	Q99750	CSNK1G3	Homo sapiens	Q9Y6M4-3	Validated Y2H	32296183
Intra	MDFI	Q99750	CEP57L1	Homo sapiens	Q8IYX8	Y2H Array	25416956
Intra	MDFI	Q99750	CEP57L1	Homo sapiens	Q8IYX8	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	ZNF230	Homo sapiens	Q9UIE0	Y2H Array	25416956
Intra	MDFI	Q99750	ZNF230	Homo sapiens	Q9UIE0	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	ZNF490	Homo sapiens	Q9ULM2	Validated Y2H	32296183
Intra	MDFI	Q99750	ZNF490	Homo sapiens	Q9ULM2	Y2H	21516116
Intra	MDFI	Q99750	ZNF490	Homo sapiens	Q9ULM2	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	ZNF490	Homo sapiens	Q9ULM2	Validated Y2H	25416956
Intra	MDFI	Q99750	ZNF696	Homo sapiens	Q9H7X3	Anti Tag CoIP	33961781
Intra	MDFI	Q99750	ZNF696	Homo sapiens	Q9H7X3	Validated Y2H	32296183
Intra	MDFI	Q99750	METTL17	Homo sapiens	Q9H7H0-2	Validated Y2H	32296183
Intra	MDFI	Q99750	FOXD4L1	Homo sapiens	Q9NU39	Validated Y2H	32296183
Intra	MDFI	Q99750	BANP	Homo sapiens	Q8N9N5-2	Validated Y2H	32296183
Intra	MDFI	Q99750	SHFL	Homo sapiens	Q9NUL5-4	Validated Y2H	32296183
Intra	MDFI	Q99750	HAPLN2	Homo sapiens	Q9GZV7	Validated Y2H	32296183
Intra	MDFI	Q99750	PRR34	Homo sapiens	Q9NV39	Validated Y2H	32296183
Intra	MDFI	Q99750	GPATCH2L	Homo sapiens	Q9NWQ4-1	Validated Y2H	32296183
Intra	MDFI	Q99750	ZIM2	Homo sapiens	Q9NZV7	Validated Y2H	32296183
Intra	MDFI	Q99750	GNE	Homo sapiens	Q9Y223-2	Validated Y2H	32296183
Intra	MDFI	Q99750	TNP2	Homo sapiens	Q05952	Y2H Array	31515488
Intra	MDFI	Q99750	ANKRD13C-DT	Homo sapiens	Q9XRX5-2	Validated Y2H	32296183
Intra	MDFI	Q99750	NUFIP2	Homo sapiens	Q7Z417	Anti Tag CoIP	33961781
Intra	MDFI	Q99750	VHL	Homo sapiens	P40337-2	Y2H Array	31515488
Intra	MDFI	Q99750	ABHD11	Homo sapiens	Q8NFV4-4	Y2H Prey Pooling	32296183
Intra	MDFI	Q99750	ZNF221	Homo sapiens	Q9UK13	Validated Y2H	32296183
Intra	MDFI	Q99750	KIAA0040	Homo sapiens	A0A384DVV8	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	GDF15	Homo sapiens	Q99988	Y2H Array	19060904
Intra	MDFI	Q99750	GDF15	Homo sapiens	Q99988	Validated Y2H	32296183
Intra	MDFI	Q99750	GDF15	Homo sapiens	Q99988	Y2H Pooling	19060904
Intra	MDFI	Q99750	SPON1	Homo sapiens	Q9HCB6	Validated Y2H	32296183
Intra	MDFI	Q99750	USP20	Homo sapiens	Q9Y2K6	Y2H Array	25416956
Intra	MDFI	Q99750	ZNF124	Homo sapiens	Q15973	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	FAM27E3	Homo sapiens	Q08E93	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	FAM27E3	Homo sapiens	Q08E93	Validated Y2H	25416956
Intra	MDFI	Q99750	GATA2	Homo sapiens	P23769	Y2H Array	31515488
Intra	MDFI	Q99750	GATA2	Homo sapiens	P23769	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	ZNF264	Homo sapiens	Q14C61	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	ZNF264	Homo sapiens	Q14C61	Validated Y2H	25416956
Intra	MDFI	Q99750	TXN2	Homo sapiens	Q99757	Validated Y2H	32296183
Intra	MDFI	Q99750	VHL	Homo sapiens	P40337	Y2H Array	31515488
Intra	MDFI	Q99750	VHL	Homo sapiens	P40337	Y2H Array	25416956
Intra	MDFI	Q99750	VHL	Homo sapiens	P40337	Validated Y2H	25416956
Intra	MDFI	Q99750	ARHGAP32	Homo sapiens	A7KAX9	Y2H Array	25416956
Intra	MDFI	Q99750	ZNF408	Homo sapiens	Q9H9D4	Validated Y2H	32296183
Intra	MDFI	Q99750	ZNF408	Homo sapiens	Q9H9D4	Y2H Pooling	16189514
Intra	MDFI	Q99750	KPNA2	Homo sapiens	P52292	Y2H Array	25416956
Intra	MDFI	Q99750	KPNA2	Homo sapiens	P52292	Validated Y2H	25416956
Intra	MDFI	Q99750	GNAI2	Homo sapiens	P04899	Validated Y2H	25416956
Intra	MDFI	Q99750	GNAI2	Homo sapiens	P04899	Y2H Array	25416956
Intra	MDFI	Q99750	GNAI2	Homo sapiens	P04899	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	RHOXF2	Homo sapiens	Q9BQY4	Validated Y2H	32296183
Intra	MDFI	Q99750	ZNF330	Homo sapiens	Q9Y3S2	Validated Y2H	32296183
Intra	MDFI	Q99750	SPRY1	Homo sapiens	O43609	MAPPIT	32296183
Intra	MDFI	Q99750	SPRY1	Homo sapiens	O43609	Validated Y2H	25416956
Intra	MDFI	Q99750	CDKL3	Homo sapiens	Q8IVW4	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	TYRO3	Homo sapiens	Q06418	Y2H Array	25416956
Intra	MDFI	Q99750	TYRO3	Homo sapiens	Q06418	Validated Y2H	25416956
Intra	MDFI	Q99750	TYRO3	Homo sapiens	Q06418	Y2H Prey Pooling	25416956
Cross	MDFI	Q99750	Hoxa1	Mus musculus	P09022	BiFC	23088713
Cross	MDFI	Q99750	Hoxa1	Mus musculus	P09022	Y2H	23088713
Intra	MDFI	Q99750	KAT5	Homo sapiens	Q92993	Y2H Array	25416956
Intra	MDFI	Q99750	VPS72	Homo sapiens	Q15906	Y2H Pooling	16189514
Intra	MDFI	Q99750	VPS72	Homo sapiens	Q15906	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	VPS72	Homo sapiens	Q15906	Validated Y2H	25416956
Intra	MDFI	Q99750	PELI2	Homo sapiens	Q9HAT8	Validated Y2H	32296183
Intra	MDFI	Q99750	DOCK2	Homo sapiens	Q92608	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	DOCK2	Homo sapiens	Q92608	Validated Y2H	25416956
Intra	MDFI	Q99750	DOCK2	Homo sapiens	Q92608	Y2H Array	25416956
Intra	MDFI	Q99750	PIDD1	Homo sapiens	Q9HB75	Y2H Array	19060904
Intra	MDFI	Q99750	PIDD1	Homo sapiens	Q9HB75	Y2H Pooling	19060904
Intra	MDFI	Q99750	PIDD1	Homo sapiens	Q9HB75	Y2H Pooling	16189514
Intra	MDFI	Q99750	ZNF101	Homo sapiens	Q8IZC7	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	ZNF101	Homo sapiens	Q8IZC7	Y2H Array	25416956
Intra	MDFI	Q99750	HNRNPLL	Homo sapiens	Q8WVV9	Y2H Array	25416956
Intra	MDFI	Q99750	HNRNPLL	Homo sapiens	Q8WVV9	Y2H	21516116
Intra	MDFI	Q99750	HNRNPLL	Homo sapiens	Q8WVV9	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	MAGEF1	Homo sapiens	Q9HAY2	Y2H Array	31515488
Intra	MDFI	Q99750	MAGEF1	Homo sapiens	Q9HAY2	Validated Y2H	25416956
Intra	MDFI	Q99750	MAGEF1	Homo sapiens	Q9HAY2	Y2H Array	25416956
Intra	MDFI	Q99750	MAGEF1	Homo sapiens	Q9HAY2	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	GPATCH2L	Homo sapiens	Q9NWQ4	Validated Y2H	25416956
Intra	MDFI	Q99750	FOXD4L6	Homo sapiens	Q3SYB3	Validated Y2H	25416956
Intra	MDFI	Q99750	LCE3D	Homo sapiens	Q9BYE3	Validated Y2H	32296183
Intra	MDFI	Q99750	ZNF266	Homo sapiens	Q14584	Validated Y2H	25416956
Intra	MDFI	Q99750	ZNF266	Homo sapiens	Q14584	Y2H Array	25416956
Intra	MDFI	Q99750	CBX8	Homo sapiens	Q9HC52	Validated Y2H	32296183
Intra	MDFI	Q99750	PIN1	Homo sapiens	Q13526	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	PIN1	Homo sapiens	Q13526	Y2H Pooling	16189514
Intra	MDFI	Q99750	TGIF1	Homo sapiens	Q15583	Y2H Array	25416956
Intra	MDFI	Q99750	TGIF1	Homo sapiens	Q15583	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	C8orf33	Homo sapiens	Q9H7E9	Y2H Array	19060904
Intra	MDFI	Q99750	C8orf33	Homo sapiens	Q9H7E9	Y2H Pooling	19060904
Intra	MDFI	Q99750	C8orf33	Homo sapiens	Q9H7E9	Validated Y2H	32296183
Intra	MDFI	Q99750	MAGED1	Homo sapiens	Q9Y5V3	Validated Y2H	32296183
Intra	MDFI	Q99750	MAGED1	Homo sapiens	Q9Y5V3	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	BEX1	Homo sapiens	Q9HBH7	Y2H Array	25416956
Intra	MDFI	Q99750	BEX1	Homo sapiens	Q9HBH7	Validated Y2H	32296183
Intra	MDFI	Q99750	BEX1	Homo sapiens	Q9HBH7	Validated Y2H	25416956
Intra	MDFI	Q99750	SPG7	Homo sapiens	Q9UQ90	Y2H Pooling	16189514
Intra	MDFI	Q99750	SPG7	Homo sapiens	Q9UQ90	Validated Y2H	25416956
Intra	MDFI	Q99750	NECTIN2	Homo sapiens	Q92692	Y2H Pooling	16189514
Intra	MDFI	Q99750	NECTIN2	Homo sapiens	Q92692	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	LRCH4	Homo sapiens	O75427	Y2H Array	19060904
Intra	MDFI	Q99750	LRCH4	Homo sapiens	O75427	Y2H Pooling	19060904
Intra	MDFI	Q99750	FBXO34	Homo sapiens	Q9NWN3	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	FBXO34	Homo sapiens	Q9NWN3	Y2H Array	25416956
Intra	MDFI	Q99750	FAM161A	Homo sapiens	Q3B820	Validated Y2H	25416956
Intra	MDFI	Q99750	FAM161A	Homo sapiens	Q3B820	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	PTPMT1	Homo sapiens	Q8WUK0	Y2H Array	25416956
Intra	MDFI	Q99750	ZNF136	Homo sapiens	P52737	Y2H Pooling	19060904
Intra	MDFI	Q99750	ZNF136	Homo sapiens	P52737	Y2H Array	19060904
Intra	MDFI	Q99750	ZNF136	Homo sapiens	P52737	Y2H Pooling	16189514
Intra	MDFI	Q99750	ZNF440	Homo sapiens	Q8IYI8	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	ZNF440	Homo sapiens	Q8IYI8	Validated Y2H	25416956
Intra	MDFI	Q99750	ZNF136	Homo sapiens	P52737	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	ZNF136	Homo sapiens	P52737	Y2H Array	25416956
Intra	MDFI	Q99750	ZNF440	Homo sapiens	Q8IYI8	Y2H Array	25416956
Intra	MDFI	Q99750	ZNF440	Homo sapiens	Q8IYI8	Y2H Pooling	16189514
Intra	MDFI	Q99750	C22orf39	Homo sapiens	Q6P5X5	Validated Y2H	25416956
Intra	MDFI	Q99750	C22orf39	Homo sapiens	Q6P5X5	Y2H Array	25416956
Intra	MDFI	Q99750	PHLDA1	Homo sapiens	Q8WV24	Y2H Pooling	16189514
Intra	MDFI	Q99750	CRACR2A	Homo sapiens	Q9BSW2	Validated Y2H	32296183
Intra	MDFI	Q99750	ZBTB25	Homo sapiens	P24278	Pull Down	16189514
Intra	MDFI	Q99750	ZBTB25	Homo sapiens	P24278	Y2H Pooling	16189514
Intra	MDFI	Q99750	b4dna4_human	Homo sapiens	B4DNA4	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	b4dna4_human	Homo sapiens	B4DNA4	Y2H Array	25416956
Intra	MDFI	Q99750	ZNF446	Homo sapiens	Q9NWS9-2	Validated Y2H	32296183
Intra	MDFI	Q99750	OTX1	Homo sapiens	P32242	BFG-2H	27107012
Intra	MDFI	Q99750	OTX1	Homo sapiens	P32242	Y2H Pooling	16189514
Intra	MDFI	Q99750	OTX1	Homo sapiens	P32242	Validated Y2H	27107012
Intra	MDFI	Q99750	DCAF8	Homo sapiens	Q5TAQ9	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	DCAF8	Homo sapiens	Q5TAQ9	Y2H Array	19060904
Intra	MDFI	Q99750	DCAF8	Homo sapiens	Q5TAQ9	Y2H Pooling	19060904
Intra	MDFI	Q99750	DCAF8	Homo sapiens	Q5TAQ9	Y2H Pooling	16189514
Intra	MDFI	Q99750	DCAF8	Homo sapiens	Q5TAQ9	Validated Y2H	25416956
Intra	MDFI	Q99750	ZNF417	Homo sapiens	Q8TAU3	Y2H Array	25416956
Intra	MDFI	Q99750	ZNF417	Homo sapiens	Q8TAU3	Y2H Pooling	16189514
Intra	MDFI	Q99750	ZNF417	Homo sapiens	Q8TAU3	Validated Y2H	25416956
Intra	MDFI	Q99750	HOXA1	Homo sapiens	P49639	Y2H Pooling	21653829
Intra	MDFI	Q99750	CCDC185	Homo sapiens	Q8N715	Y2H Pooling	16189514
Intra	MDFI	Q99750	RASD1	Homo sapiens	Q9Y272	Validated Y2H	32296183
Intra	MDFI	Q99750	PBXIP1	Homo sapiens	Q96AQ6	Y2H Array	19060904
Intra	MDFI	Q99750	PBXIP1	Homo sapiens	Q96AQ6	Y2H Pooling	19060904
Intra	MDFI	Q99750	PBXIP1	Homo sapiens	Q96AQ6	Y2H Array	29892012
Intra	MDFI	Q99750	PBXIP1	Homo sapiens	Q96AQ6	Y2H Array	31515488
Intra	MDFI	Q99750	CNNM3	Homo sapiens	Q8NE01	Y2H Pooling	16189514
Intra	MDFI	Q99750	FAM124B	Homo sapiens	Q9H5Z6	Y2H Pooling	16189514
Intra	MDFI	Q99750	RABL6	Homo sapiens	Q3YEC7	Y2H Pooling	16189514
Intra	MDFI	Q99750	TYMSOS	Homo sapiens	Q8TAI1	Y2H Pooling	16189514
Intra	MDFI	Q99750	ELOA	Homo sapiens	Q14241	Validated Y2H	25416956
Intra	MDFI	Q99750	ELOA	Homo sapiens	Q14241	Y2H Array	25416956
Intra	MDFI	Q99750	SPRY2	Homo sapiens	O43597	Validated Y2H	25416956
Intra	MDFI	Q99750	BAHD1	Homo sapiens	Q8TBE0	Y2H Array	25416956
Intra	MDFI	Q99750	BAHD1	Homo sapiens	Q8TBE0	Y2H Pooling	16189514
Intra	MDFI	Q99750	BAHD1	Homo sapiens	Q8TBE0	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	LASP1	Homo sapiens	Q14847	Y2H Pooling	16189514
Intra	MDFI	Q99750	DKK1	Homo sapiens	O94907	Y2H Pooling	16189514
Intra	MDFI	Q99750	DKK1	Homo sapiens	O94907	Y2H Array	31515488
Intra	MDFI	Q99750	ARMC7	Homo sapiens	Q9H6L4	Validated Y2H	32296183
Intra	MDFI	Q99750	SIX1	Homo sapiens	Q15475	Y2H Pooling	16189514
Intra	MDFI	Q99750	C10orf62	Homo sapiens	Q5T681	Y2H Array	25416956
Intra	MDFI	Q99750	C10orf62	Homo sapiens	Q5T681	Y2H Pooling	16189514
Intra	MDFI	Q99750	ENKD1	Homo sapiens	Q9H0I2	Y2H Array	25416956
Intra	MDFI	Q99750	ENKD1	Homo sapiens	Q9H0I2	Y2H Pooling	16189514
Intra	MDFI	Q99750	ENKD1	Homo sapiens	Q9H0I2	Validated Y2H	32296183
Intra	MDFI	Q99750	CCDC116	Homo sapiens	Q8IYX3	Y2H Pooling	16189514
Intra	MDFI	Q99750	FBXL18	Homo sapiens	Q96D16	Validated Y2H	25416956
Intra	MDFI	Q99750	FBXL18	Homo sapiens	Q96D16	Y2H Array	25416956
Intra	MDFI	Q99750	ZBTB24	Homo sapiens	O43167	Y2H Pooling	16189514
Intra	MDFI	Q99750	ZBTB24	Homo sapiens	O43167	Y2H Array	25416956
Intra	MDFI	Q99750	CATSPER1	Homo sapiens	Q8NEC5	Y2H Pooling	16189514
Intra	MDFI	Q99750	FNDC11	Homo sapiens	Q9BVV2	Validated Y2H	25416956
Intra	MDFI	Q99750	FNDC11	Homo sapiens	Q9BVV2	Y2H Array	25416956
Intra	MDFI	Q99750	FNDC11	Homo sapiens	Q9BVV2	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	BEX2	Homo sapiens	Q9BXY8	Validated Y2H	32296183
Intra	MDFI	Q99750	BEX2	Homo sapiens	Q9BXY8	MAPPIT	32296183
Intra	MDFI	Q99750	AANAT	Homo sapiens	Q16613	Validated Y2H	25416956
Intra	MDFI	Q99750	AANAT	Homo sapiens	Q16613	Y2H Array	25416956
Intra	MDFI	Q99750	AANAT	Homo sapiens	Q16613	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	AQP1	Homo sapiens	P29972	Y2H Pooling	19447967
Intra	MDFI	Q99750	AQP1	Homo sapiens	P29972	Y2H Array	19060904
Intra	MDFI	Q99750	AQP1	Homo sapiens	P29972	Y2H Pooling	19060904
Intra	MDFI	Q99750	ZNF670	Homo sapiens	Q9BS34	Validated Y2H	32296183
Intra	MDFI	Q99750	ZNF670	Homo sapiens	Q9BS34	Y2H Pooling	19060904
Intra	MDFI	Q99750	NR1H2	Homo sapiens	P55055	Y2H Pooling	16189514
Intra	MDFI	Q99750	ZNF581	Homo sapiens	Q9P0T4	Validated Y2H	25416956
Intra	MDFI	Q99750	ZNF581	Homo sapiens	Q9P0T4	Validated Y2H	32296183
Intra	MDFI	Q99750	ZNF581	Homo sapiens	Q9P0T4	Y2H Pooling	16189514
Intra	MDFI	Q99750	ZNF679	Homo sapiens	Q8IYX0	Y2H Pooling	16189514
Intra	MDFI	Q99750	ZNF646	Homo sapiens	O15015	Y2H Pooling	16189514
Intra	MDFI	Q99750	ATOSB	Homo sapiens	Q7L5A3	Y2H Array	29892012
Intra	MDFI	Q99750	ZNF764	Homo sapiens	Q96H86	Y2H Pooling	16189514
Intra	MDFI	Q99750	REX1BD	Homo sapiens	Q96EN9	Y2H Pooling	19060904
Intra	MDFI	Q99750	REX1BD	Homo sapiens	Q96EN9	Y2H Pooling	16189514
Intra	MDFI	Q99750	REX1BD	Homo sapiens	Q96EN9	Y2H Array	19060904
Intra	MDFI	Q99750	CBX2	Homo sapiens	Q14781	Y2H Pooling	16189514
Intra	MDFI	Q99750	ZNF580	Homo sapiens	Q9UK33	Validated Y2H	32296183
Intra	MDFI	Q99750	DHRS1	Homo sapiens	Q96LJ7	Y2H Pooling	16189514
Intra	MDFI	Q99750	ZNF559	Homo sapiens	Q9BR84	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	ZNF559	Homo sapiens	Q9BR84	Validated Y2H	25416956
Intra	MDFI	Q99750	ZNF559	Homo sapiens	Q9BR84	Validated Y2H	32296183
Intra	MDFI	Q99750	ZNF559	Homo sapiens	Q9BR84	Y2H Array	29892012
Intra	MDFI	Q99750	ZNF559	Homo sapiens	Q9BR84	Y2H Pooling	16189514
Intra	MDFI	Q99750	TNNI1	Homo sapiens	P19237	Validated Y2H	25416956
Intra	MDFI	Q99750	TNNI1	Homo sapiens	P19237	Y2H Array	25416956
Intra	MDFI	Q99750	NEU4	Homo sapiens	Q8WWR8	Y2H Pooling	19060904
Intra	MDFI	Q99750	NEU4	Homo sapiens	Q8WWR8	Y2H Array	19060904
Intra	MDFI	Q99750	NEU4	Homo sapiens	Q8WWR8	Y2H Pooling	19447967
Intra	MDFI	Q99750	ZNF607	Homo sapiens	Q96SK3	Y2H Pooling	16189514
Intra	MDFI	Q99750	ZNF607	Homo sapiens	Q96SK3	Y2H Array	25416956
Intra	MDFI	Q99750	ZNF439	Homo sapiens	Q8NDP4	Validated Y2H	25416956
Intra	MDFI	Q99750	ZNF439	Homo sapiens	Q8NDP4	Y2H Array	25416956
Intra	MDFI	Q99750	ZNF439	Homo sapiens	Q8NDP4	Y2H	21516116
Intra	MDFI	Q99750	ZNF439	Homo sapiens	Q8NDP4	Y2H Pooling	16189514
Intra	MDFI	Q99750	TACO1	Homo sapiens	Q9BSH4	Validated Y2H	32296183
Intra	MDFI	Q99750	ZNF707	Homo sapiens	Q96C28	Y2H Pooling	16189514
Intra	MDFI	Q99750	ZNF707	Homo sapiens	Q96C28	Y2H Pooling	19447967
Intra	MDFI	Q99750	BBS2	Homo sapiens	Q9BXC9	Validated Y2H	32296183
Intra	MDFI	Q99750	BBS2	Homo sapiens	Q9BXC9	MAPPIT	32296183
Intra	MDFI	Q99750	SCNM1	Homo sapiens	Q9BWG6	Validated Y2H	32296183
Intra	MDFI	Q99750	CBFA2T2	Homo sapiens	O43439	Y2H Array	19060904
Intra	MDFI	Q99750	CBFA2T2	Homo sapiens	O43439	Y2H Pooling	19060904
Intra	MDFI	Q99750	CBFA2T2	Homo sapiens	O43439	Y2H Pooling	16189514
Intra	MDFI	Q99750	CBFA2T2	Homo sapiens	O43439	Y2H	21516116
Intra	MDFI	Q99750	NPDC1	Homo sapiens	Q9NQX5	Validated Y2H	32296183
Intra	MDFI	Q99750	NPDC1	Homo sapiens	Q9NQX5	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	NPDC1	Homo sapiens	Q9NQX5	Validated Y2H	25416956
Intra	MDFI	Q99750	NPDC1	Homo sapiens	Q9NQX5	Y2H Pooling	16189514
Intra	MDFI	Q99750	METTL17	Homo sapiens	Q9H7H0	Y2H Array	29892012
Intra	MDFI	Q99750	METTL17	Homo sapiens	Q9H7H0	Y2H Pooling	16189514
Intra	MDFI	Q99750	ZFAB	Homo sapiens	Q9Y260	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	ZFAB	Homo sapiens	Q9Y260	Y2H Array	25416956
Intra	MDFI	Q99750	ZFAB	Homo sapiens	Q9Y260	Y2H Pooling	16189514
Intra	MDFI	Q99750	SLC25A10	Homo sapiens	Q9UBX3	Y2H Pooling	19447967
Intra	MDFI	Q99750	SLC25A10	Homo sapiens	Q9UBX3	Validated Y2H	25416956
Intra	MDFI	Q99750	SLC25A10	Homo sapiens	Q9UBX3	Y2H Array	19060904
Intra	MDFI	Q99750	SLC25A10	Homo sapiens	Q9UBX3	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	SLC25A10	Homo sapiens	Q9UBX3	Y2H Array	25416956
Intra	MDFI	Q99750	SLC25A10	Homo sapiens	Q9UBX3	Y2H Pooling	19060904
Intra	MDFI	Q99750	SPMAP2	Homo sapiens	Q9P2T0	Y2H Pooling	19060904
Intra	MDFI	Q99750	SPMAP2	Homo sapiens	Q9P2T0	Y2H Pooling	16189514
Intra	MDFI	Q99750	SPMAP2	Homo sapiens	Q9P2T0	Y2H Array	19060904
Intra	MDFI	Q99750	HEYL	Homo sapiens	Q9NQ87	Validated Y2H	32296183
Intra	MDFI	Q99750	HEYL	Homo sapiens	Q9NQ87	Y2H Array	25416956
Intra	MDFI	Q99750	C8orf48	Homo sapiens	Q96LL4	Y2H Pooling	16189514
Intra	MDFI	Q99750	NR1H3	Homo sapiens	Q13133	Y2H Array	25416956
Intra	MDFI	Q99750	NR1H3	Homo sapiens	Q13133	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	TTLL10	Homo sapiens	Q6ZVT0	Y2H Array	25416956
Intra	MDFI	Q99750	WNT11	Homo sapiens	O96014	Validated Y2H	25416956
Intra	MDFI	Q99750	WNT11	Homo sapiens	O96014	Y2H Array	25416956
Intra	MDFI	Q99750	SPATA8	Homo sapiens	Q6RVD6	Validated Y2H	25416956
Intra	MDFI	Q99750	AVPI1	Homo sapiens	Q5T686	Y2H	21516116
Intra	MDFI	Q99750	AVPI1	Homo sapiens	Q5T686	Y2H Array	25416956
Intra	MDFI	Q99750	ZFYVE26	Homo sapiens	Q68DK2-5	Validated Y2H	25416956
Intra	MDFI	Q99750	ZFYVE26	Homo sapiens	Q68DK2-5	MAPPIT	32296183
Intra	MDFI	Q99750	DNMT3A	Homo sapiens	Q9Y6K1	Validated Y2H	32296183
Intra	MDFI	Q99750	MAPKBP1	Homo sapiens	O60336	Validated Y2H	25416956
Intra	MDFI	Q99750	PLEKHG4	Homo sapiens	Q58EX7	Y2H Array	25416956
Intra	MDFI	Q99750	PDIA5	Homo sapiens	Q14554	Y2H Prey Pooling	25416956
Intra	MDFI	Q99750	DMRT3	Homo sapiens	Q9NQL9	Validated Y2H	25416956
Intra	MDFI	Q99750	DMRT3	Homo sapiens	Q9NQL9	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Erythema Infectiosum

Fifth Disease	Slapped Cheek Syndrome
Parvovirus B19 Infection

Viral Exanthem

Viral Rash Nos	Virus Exanthema
Nonspecific Exanthematous Viral Infection	Nonspecific Viral Exanthem
Nonspecific Viral Rash	Viral Enanthema Nos
Viral Disease Characterised By Exanthem	Viral Exanthemata
Viral Exanthem, Unspecified	Viral Exanthema Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08256	MDFI Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	MDFI	VGNC	VGNC:74689
Felis catus	MDFI	VGNC	VGNC:68219
Bos taurus	MDFI	VGNC	VGNC:31329
Mus musculus	MDFI	MGD	MGI:107687
Rattus norvegicus	MDFI	RGD	RGD:1560271
Canis familiaris	MDFI	VGNC	VGNC:43099

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