2. Gene
  3. ANP32B - acidic nuclear phosphoprotein 32 family member B Gene

ANP32B - acidic nuclear phosphoprotein 32 family member B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as APRIL; SSP29; PHAPI2

Gene ID: 10541 | Gene type: protein coding

About ANP32B

Cytogenetic location: 9q22.33 Genomic coordinates (GRCh38): 9:97,983,341-98,015,943 (from NCBI)

This gene has 3 transcripts (splice variants), 302 orthologues and 3 paralogues. Ubiquitous expression in bone marrow (RPKM 88.8), lymph node (RPKM 73.8) and 25 other tissues.

Summary

Enables RNA polymerase binding activity and histone binding activity. Involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; nucleosome assembly; and positive regulation of protein export from nucleus. Located in cytoplasm and nucleoplasm. Colocalizes with nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

ANP32B Products(1)

mRNA Protein Name
NM_006401.3 NP_006392.1 acidic leucine-rich nuclear phosphoprotein 32 family member B

ANP32B Protein Structure

LRR_9

LRR_9: Leucine-rich repeat (17 - 149)

  • 0
  • 100
  • 200
  • 251 a.a.
Protein Preferred Names Protein Names

acidic leucine-rich nuclear phosphoprotein 32 family member B

acidic (leucine-rich) nuclear phosphoprotein 32 family, member B

Related Diseases

Diseases Alias
Influenza

Flu

Influenza With Non-Respiratory Manifestation

Influenza With Other Manifestations

Influenza, Human

Influenza, Susceptibility To

Seasonal Influenza, Virus Identified
Myopathy, Congenital, Compton-North

Compton-North Congenital Myopathy

MYPCN

Congenital Lethal Myopathy, Compton-North Type
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00752 ANP32B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ANP32B VGNC VGNC:59835
Rattus norvegicus ANP32B RGD RGD:621285
Macaca mulatta ANP32B VGNC VGNC:103240
Canis familiaris ANP32B VGNC VGNC:37933
Bos taurus ANP32B VGNC VGNC:25958
Mus musculus ANP32B MGD MGI:1914878