2. Gene
  3. CD300A - CD300a molecule Gene

CD300A - CD300a molecule Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as IRC1; IRC2; CLM-8; IRp60; IGSF12; CMRF35H; CMRF-35H; CMRF35-H; CMRF35H9; CMRF35-H9; IRC1/IRC2; CMRF-35-H9

Gene ID: 11314 | Gene type: protein coding

About CD300A

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:74,466,373-74,484,798 (from NCBI)

This gene has 7 transcripts (splice variants), 91 orthologues and 13 paralogues. Broad expression in spleen (RPKM 24.5), appendix (RPKM 12.1) and 14 other tissues.

Summary

This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. This gene is located on chromosome 17 in a cluster with all but one of the other family members. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

CD300A Products(4)

mRNA Protein Name
NM_001256841.2 NP_001243770.1 CMRF35-like molecule 8 isoform 2 precursor
NM_001330456.1 NP_001317385.1 CMRF35-like molecule 8 isoform 3
NM_001330457.2 NP_001317386.1 CMRF35-like molecule 8 isoform 4 precursor
NM_007261.4 NP_009192.2 CMRF35-like molecule 8 isoform 1 precursor

CD300A Protein Structure

V-set

V-set: Immunoglobulin V-set domain (19 - 112)

SIT

SIT: SHP2-interacting transmembrane adaptor protein, SIT (181 - 275)

  • 0
  • 100
  • 200
  • 299 a.a.
Protein Preferred Names Protein Names

CMRF35-like molecule 8

CD300 antigen-like family member A

Recombinant CD300A Proteins

Cat. No. Product Name Accession Purity
HY-P70754 CD300a/LMIR1 Protein, Human (HEK293, Fc-His) Q9UGN4-1 (L18-Q178) ≥95%
HY-P72738 CD300a/LMIR1 Protein, Human (HEK293, His) Q9UGN4-1 (L18-Q178) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02226 CD300A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CD300A RGD RGD:1583719
Macaca mulatta CD300A VGNC VGNC:104592
Mus musculus CD300A MGD MGI:2443411
Macaca fascicularis CD300A NCBI NCBI:102124907
Others CD300A NCBI