2. Gene
  3. CD300A - CD300a molecule Gene

CD300A - CD300a molecule Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as IRC1; IRC2; CLM-8; IRp60; IGSF12; CMRF35H; CMRF-35H; CMRF35-H; CMRF35H9; CMRF35-H9; IRC1/IRC2; CMRF-35-H9

Gene ID: 11314 | Gene type: protein coding

About CD300A

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:74,466,373-74,484,798 (from NCBI)

This gene has 7 transcripts (splice variants), 91 orthologues and 13 paralogues. Broad expression in spleen (RPKM 24.5), appendix (RPKM 12.1) and 14 other tissues.

Summary

This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. This gene is located on chromosome 17 in a cluster with all but one of the Other family members. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

CD300A Products(4)

mRNA Protein Name
NM_001256841.2 NP_001243770.1 CMRF35-like molecule 8 isoform 2 precursor
NM_001330456.1 NP_001317385.1 CMRF35-like molecule 8 isoform 3
NM_001330457.2 NP_001317386.1 CMRF35-like molecule 8 isoform 4 precursor
NM_007261.4 NP_009192.2 CMRF35-like molecule 8 isoform 1 precursor

CD300A Protein Structure

V-set

V-set: Immunoglobulin V-set domain (19 - 112)

SIT

SIT: SHP2-interacting transmembrane adaptor protein, SIT (181 - 275)

  • 0
  • 100
  • 200
  • 299 a.a.
Protein Preferred Names Protein Names

CMRF35-like molecule 8

CD300 antigen-like family member A

CD300A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
CD300A Q9UGN4 KRT38 Homo sapiens O76015
Y2H Array
25416956
Intra
CD300A Q9UGN4 KRT38 Homo sapiens O76015
Y2H Prey Pooling
25416956
Intra
CD300A Q9UGN4 CD300LB Homo sapiens A8K4G0
Anti Tag CoIP
20959446
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CD300A Proteins

Cat. No. Product Name Accession Purity
HY-P70754 CD300a/LMIR1 Protein, Human (HEK293, Fc-His) Q9UGN4-1 (L18-Q178) ≥95%
HY-P72738 CD300a/LMIR1 Protein, Human (HEK293, His) Q9UGN4-1 (L18-Q178) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02226 CD300A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CD300A RGD RGD:1583719
Macaca mulatta CD300A VGNC VGNC:104592
Mus musculus CD300A MGD MGI:2443411
Macaca fascicularis CD300A NCBI NCBI:102124907
Others CD300A NCBI