CD300LB - CD300 molecule like family member b Gene

Homo sapiens

Also known as CLM7; CLM-7; IREM3; TREM5; CD300b; IREM-3; TREM-5; CMRF35-A2

Gene ID: 124599 | Gene type: protein coding

About CD300LB

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:74,521,174-74,531,475 (from NCBI)

This gene has 2 transcripts (splice variants), 73 orthologues and 13 paralogues. Biased expression in appendix (RPKM 4.4), bone marrow (RPKM 2.5) and 11 other tissues.

Summary

CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]).[supplied by OMIM, Mar 2008]

CD300LB Products(1)

mRNA	Protein	Name
NM_174892.4	NP_777552.3	CMRF35-like molecule 7 precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	20959446	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	20959446	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CD300LB Protein Structure

V-set

0
100
200
238 a.a.

Protein Preferred Names

Protein Names

CMRF35-like molecule 7

CD300 antigen like family member B

CD300LB Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CD300LB	A8K4G0	CD300A	Homo sapiens	Q9UGN4	Anti Tag CoIP	29051512
Intra	CD300LB	A8K4G0	CD300E	Homo sapiens	Q496F6	Anti Tag CoIP	20959446
Intra	CD300LB	A8K4G0	CD300E	Homo sapiens	Q496F6	Anti Tag CoIP	29051512
Intra	CD300LB	A8K4G0	CD300LF	Homo sapiens	Q8TDQ1	Anti Tag CoIP	20959446
Intra	CD300LB	A8K4G0	ATP2B2	Homo sapiens	Q01814	Anti Tag CoIP	33961781
Intra	CD300LB	A8K4G0	CD300C	Homo sapiens	Q08708	Anti Tag CoIP	20959446
Intra	CD300LB	A8K4G0	CD300LB	Homo sapiens	A8K4G0	Anti Tag CoIP	29051512
Intra	CD300LB	A8K4G0	CD300LF	Homo sapiens	Q8TDQ1	Anti Tag CoIP	29051512
Intra	CD300LB	A8K4G0	CD300LB	Homo sapiens	A8K4G0	Anti Tag CoIP	20959446
Intra	CD300LB	A8K4G0	RAD51B	Homo sapiens	O15315	Anti Tag CoIP	33961781
Intra	CD300LB	A8K4G0	CD300LD	Homo sapiens	Q6UXZ3	Anti Tag CoIP	22291008
Intra	CD300LB	A8K4G0	CD300C	Homo sapiens	Q08708	Anti Tag CoIP	29051512
Intra	CD300LB	A8K4G0	DDX19B	Homo sapiens	Q9UMR2	Anti Tag CoIP	33961781
Intra	CD300LB	A8K4G0	ATP13A1	Homo sapiens	Q9HD20	Anti Tag CoIP	33961781
Intra	CD300LB	A8K4G0	CD300LD	Homo sapiens	Q6UXZ3	Anti Tag CoIP	29051512

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CD300LB Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72774	CD300LB Protein, Human (HEK293, hFc)	AAH28091.1 (I55-H187)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02229	CD300LB Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	CD300LB	VGNC	VGNC:99135
Rattus norvegicus	CD300LB	RGD	RGD:1583718
Mus musculus	CD300LB	MGD	MGI:2685099
Others	CD300LB	NCBI

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