2. Gene
  3. Ccl4 - C-C motif chemokine ligand 4 Gene

Ccl4 - C-C motif chemokine ligand 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Scya4; Mip1-b

Gene ID: 116637 | Gene type: protein coding

About Ccl4

Summary

Enables chemokine activity. Involved in several processes, including leukocyte chemotaxis; positive regulation of tumor necrosis factor production; and positive regulation of vascular permeability. Predicted to be active in extracellular space. Biomarker of anti-basement membrane glomerulonephritis; obesity; and status epilepticus. Human ortholog(s) of this gene implicated in acquired immunodeficiency syndrome and human immunodeficiency virus infectious disease. Orthologous to several human genes including CCL4L2 (C-C motif chemokine ligand 4 like 2). [provided by Alliance of Genome Resources, Apr 2022]

Ccl4 Products(1)

mRNA Protein Name
NM_053858.2 NP_446310.2 C-C motif chemokine 4 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables chemokine activity IDA
IDA: Inferred from direct assay
10679105 RGD
Biological Process GO Annotation Evidence Reference Source
involved in leukocyte chemotaxis IDA
IDA: Inferred from direct assay
10679105 RGD
involved in positive regulation of tumor necrosis factor production IMP
IMP: Inferred from mutant phenotype
10679105 RGD
involved in positive regulation of vascular permeability IDA
IDA: Inferred from direct assay
10679105 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-C motif chemokine 4

MIP-1-beta

chemokine (C-C motif) ligand 4

macrophage inflammatory protein 1-beta

small-inducible cytokine A4

Recombinant Ccl4 Proteins

Cat. No. Product Name Accession Purity
HY-P71899 CCL4 Protein, Rat P50230 (A24-N92) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-B0498 Bindarit Inhibitor 99.53% Phase 3
HY-152293 EVT801 Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (26)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0330 Momordin Ic 99.71% Unkown
HY-N0823 Lithospermic acid 99.92% Unkown
HY-N0373 Licochalcone B 99.93% Unkown
HY-145801 XT2 Inhibitor 99.48% Unkown
HY-149202 UT-11 Inhibitor 99.62% Unkown
HY-N2082 Isorhamnetin 3-O-galactoside 99.64% Unkown
HY-133019 ATX inhibitor 5 Inhibitor 99.20% Unkown
HY-163897 PROTAC NCOA4 degrader-1 Inhibitor 99.42% Unkown
HY-N2109 Macranthoidin A 99.42% Unkown
HY-N2358 Blumeatin 99.37% Unkown
HY-121271 Kadsurin 99.38% Unkown
HY-N2998 Ganoderenic acid A Inhibitor 97.93% Unkown
HY-121944 Ricinine / Unkown
HY-122951 Eburicoic acid 98.97% Unkown
HY-146350 TrxR-IN-4 Inhibitor / Unkown
HY-168713 LZ-007 Agonist / Unkown
HY-N0373R Licochalcone B (Standard) / Unkown
HY-N12016 Fulvotomentoside B / Unkown
HY-N3315 Massonianoside B / Unkown
HY-N9173 Cupressuflavone / Unkown
HY-RS02102 CCL4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS02103 CCL4L1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS02104 CCL4L2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-121944S Ricinine-d3 / Unkown
HY-168629 FXR agonist 9 Inhibitor / Unkown
HY-N7327 Ochnaflavone Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccl4 NCBI NCBI:6351
Mus musculus Ccl4 NCBI NCBI:20303