Bnip3l - BCL2/adenovirus E1B interacting protein 3-like Gene

Mus musculus

Also known as Nix; Nip3L; D14Ertd719e

Gene ID: 12177 | Gene type: protein coding

About Bnip3l

Summary

Enables identical protein binding activity. Involved in regulation of Autophagy of mitochondrion and regulation of protein targeting to mitochondrion. Acts upstream of or within positive regulation of apoptotic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human BNIP3L (BCL2 interacting protein 3 like). [provided by Alliance of Genome Resources, Apr 2022]

Bnip3l Products(1)

mRNA	Protein	Name
NM_009761.3	NP_033891.1	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	9867803	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	17095503	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within positive regulation of apoptotic process	IDA IDA: Inferred from direct assay	9867803	MGI
involved in regulation of mitophagy	IGI IGI: Inferred from genetic interaction	20200478	MGI
involved in regulation of protein targeting to mitochondrion	IGI IGI: Inferred from genetic interaction	20200478	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in mitochondrion	IDA IDA: Inferred from direct assay	9867803	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

BCL2/adenovirus E1B 19 kDa-interacting protein 3-like	BCL2/adenovirus E1B 19kDa-interacting protein 3-like
NIP3-like protein X

Bnip3l Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Cross	Bnip3l	Q9Z2F7	MAP1LC3B	Homo sapiens	Q9GZQ8	NMR	20010802
Cross	Bnip3l	Q9Z2F7	MAP1LC3B	Homo sapiens	Q9GZQ8	Pull Down	20010802
Cross	Bnip3l	Q9Z2F7	MAP1LC3B	Homo sapiens	Q9GZQ8	ITC	20010802
Cross	Bnip3l	Q9Z2F7	GABARAPL2	Homo sapiens	P60520	Pull Down	20010802
Cross	Bnip3l	Q9Z2F7	MAP1LC3A	Homo sapiens	Q9H492	Pull Down	20010802
Cross	Bnip3l	Q9Z2F7	MAP1LC3A	Homo sapiens	Q9H492	ITC	20010802
Cross	Bnip3l	Q9Z2F7	GABARAPL1	Homo sapiens	Q9H0R8	IF	20010802
Cross	Bnip3l	Q9Z2F7	GABARAPL1	Homo sapiens	Q9H0R8	Pull Down	20010802
Intra	Bnip3l	Q9Z2F7	Sh3rf1	Mus musculus	Q69ZI1	Y2H	17095503
Intra	Bnip3l	Q9Z2F7	Sh3rf1	Mus musculus	Q69ZI1	Anti Tag CoIP	17095503

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01565	BNIP3L Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Bnip3l	NCBI	NCBI:665

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