H3C14 - H3 clustered histone 14 Gene

Homo sapiens

Also known as H3; H3.2; H3/M; H3F2; H3FM; H3FN; H3C13; H3C15; HIST2H3C

Gene ID: 126961 | Gene type: protein coding

About H3C14

Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy. [provided by RefSeq, Aug 2015]

H3C14 Products(1)

mRNA	Protein	Name
NM_021059.3	NP_066403.2	histone H3.2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	20580717	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in nucleosome assembly	IDA IDA: Inferred from direct assay	21636898	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
part of nucleosome	IDA IDA: Inferred from direct assay	21636898	GOA
part of nucleosome	IPI IPI: Inferred from physical interaction	26694698	GOA
located in nucleus	IDA IDA: Inferred from direct assay	21636898	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

histone H3.2

H3 histone family, member M

H3C14 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	H3C13	Q71DI3	CHAF1A	Homo sapiens	Q13111	Anti Tag CoIP	23075851
Intra	H3C13	Q71DI3	JPH3	Homo sapiens	Q8WXH2	Validated Y2H	32814053
Intra	H3C13	Q71DI3	JPH3	Homo sapiens	Q8WXH2	Y2H Array	32814053
Intra	H3C13	Q71DI3	JPH3	Homo sapiens	Q8WXH2	Y2H Pooling	32814053
Intra	H3C13	Q71DI3	H2BC21	Homo sapiens	Q16778	Crosslink	30021884
Intra	H3C13	Q71DI3	DAXX	Homo sapiens	Q9UER7-1	Anti Tag CoIP	23075851
Intra	H3C13	Q71DI3	H4C16	Homo sapiens	P62805	GMS	26167883
Intra	H3C13	Q71DI3	H4C16	Homo sapiens	P62805	Light Scattering	26167883
Intra	H3C13	Q71DI3	LMNA	Homo sapiens	P02545	SPR	20580717
Intra	H3C13	Q71DI3	H3-4	Homo sapiens	Q16695	Crosslink	30021884
Intra	H3C13	Q71DI3	BPTF	Homo sapiens	Q12830-4	Pull Down	21596426
Intra	H3C13	Q71DI3	ATXN10	Homo sapiens	Q9UBB4	Validated Y2H	32814053
Intra	H3C13	Q71DI3	ATXN10	Homo sapiens	Q9UBB4	Y2H Pooling	32814053
Intra	H3C13	Q71DI3	ATXN10	Homo sapiens	Q9UBB4	Y2H Array	32814053
Intra	H3C13	Q71DI3	NASP	Homo sapiens	P49321-2	Y2H Prey Pooling	32296183
Intra	H3C13	Q71DI3	NASP	Homo sapiens	P49321-2	Y2H Array	32296183
Intra	H3C13	Q71DI3	NDUFV2	Homo sapiens	P19404	Y2H Pooling	32814053
Intra	H3C13	Q71DI3	NDUFV2	Homo sapiens	P19404	Validated Y2H	32814053
Intra	H3C13	Q71DI3	NDUFV2	Homo sapiens	P19404	Y2H Array	32814053
Intra	H3C13	Q71DI3	GFAP	Homo sapiens	P14136	Validated Y2H	32814053
Intra	H3C13	Q71DI3	GFAP	Homo sapiens	P14136	Y2H Pooling	32814053
Intra	H3C13	Q71DI3	GFAP	Homo sapiens	P14136	Y2H Array	32814053
Intra	H3C13	Q71DI3	DBH	Homo sapiens	P09172	Validated Y2H	32814053
Intra	H3C13	Q71DI3	DBH	Homo sapiens	P09172	Y2H Array	32814053
Intra	H3C13	Q71DI3	DBH	Homo sapiens	P09172	Y2H Pooling	32814053

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05967	H3C14 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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