2. Gene
  3. FUNDC1 - FUN14 domain containing 1 Gene

FUNDC1 - FUN14 domain containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 139341 | Gene type: protein coding

About FUNDC1

Cytogenetic location: Xp11.3 Genomic coordinates (GRCh38): X:44,523,639-44,542,859 (from NCBI)

This gene has 2 transcripts (splice variants), 248 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 11.4), heart (RPKM 11.0) and 25 other tissues.

Summary

This gene encodes a protein with a FUN14 superfamily domain. The function of the encoded protein is not known. [provided by RefSeq, Sep 2011]

FUNDC1 Products(1)

mRNA Protein Name
NM_173794.4 NP_776155.1 FUN14 domain-containing protein 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
20562859 GOA
Biological Process GO Annotation Evidence Reference Source
involved in autophagy of mitochondrion IDA
IDA: Inferred from direct assay
22267086 GOA
acts upstream of or within autophagy of mitochondrion IGI
IGI: Inferred from genetic interaction
22267086 GOA
acts upstream of or within autophagy of mitochondrion IMP
IMP: Inferred from mutant phenotype
22267086 GOA
involved in mitochondrial fusion IGI
IGI: Inferred from genetic interaction
37931419 GOA
involved in mitophagy IGI
IGI: Inferred from genetic interaction
34244144 GOA
involved in response to hypoxia IDA
IDA: Inferred from direct assay
22267086 GOA
acts upstream of or within response to hypoxia IMP
IMP: Inferred from mutant phenotype
22267086 GOA
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrial outer membrane IDA
IDA: Inferred from direct assay
22267086 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FUNDC1 Protein Structure

FUN14

FUN14: FUN14 family (53 - 154)

  • 0
  • 100
  • 155 a.a.
Protein Preferred Names Protein Names

FUN14 domain-containing protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05145 FUNDC1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris FUNDC1 VGNC VGNC:41007
Bos taurus FUNDC1 VGNC VGNC:29143
Mus musculus FUNDC1 MGD MGI:1919268
Rattus norvegicus FUNDC1 RGD RGD:1563372