2. Gene
  3. Glp1r - glucagon-like peptide 1 receptor Gene

Glp1r - glucagon-like peptide 1 receptor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as GLP-1R; GLP1Rc

Gene ID: 14652 | Gene type: protein coding

About Glp1r

Summary

Predicted to enable glucagon-like peptide 1 receptor activity and peptide hormone binding activity. Involved in several processes, including learning or memory; positive regulation of blood pressure; and response to psychosocial stress. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; gut; liver; and lung. Orthologous to human GLP1R (glucagon like peptide 1 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Glp1r Products(1)

mRNA Protein Name
NM_021332.2 NP_067307.2 glucagon-like peptide 1 receptor precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within positive effect hormone secretion IMP
IMP: Inferred from mutant phenotype
23542788 MGI
involved in learning or memory IMP
IMP: Inferred from mutant phenotype
12925848 MGI
acts upstream of negative regulation of blood pressure IMP
IMP: Inferred from mutant phenotype
23542788 MGI
involved in positive regulation of blood pressure IDA
IDA: Inferred from direct assay
21810595 MGI
acts upstream of or within post-translational protein targeting to membrane, translocation IMP
IMP: Inferred from mutant phenotype
23542788 MGI
involved in regulation of heart contraction IMP
IMP: Inferred from mutant phenotype
12746281 MGI
involved in response to psychosocial stress IMP
IMP: Inferred from mutant phenotype
10650957 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glucagon-like peptide 1 receptor

GLP-1 receptor

GLP-1-R

Recombinant Glp1r Proteins

Cat. No. Product Name Accession Purity
HY-P72206 GLP1R Protein, Mouse (His-SUMO) O35659 (G22-Y145) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Phase
HY-P3506 Retatrutide Agonist 99.95% Phase 3
HY-112185 Orforglipron Agonist 99.80% Phase 3
HY-P3375 Mazdutide Agonist 99.74% Phase 3
HY-P3506A Retatrutide TFA Agonist 99.31% Phase 3
HY-P3375A Mazdutide TFA Agonist / Phase 3
HY-P3506B Retatrutide acetate Agonist / Phase 3
HY-125824 Danuglipron Agonist 98.63% Phase 2
HY-P4146 Survodutide Agonist 99.83% Phase 2
HY-P3291 Dapiglutide Agonist 99.40% Phase 2
HY-P4146A Survodutide TFA Agonist 99.62% Phase 2
HY-P10019 Pegsebrenatide Agonist / Phase 2
Pre-clinical Phase
Bioactive Molecules (57)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-121835 GLP-1R agonist 2 Agonist 99.94% Unkown
HY-101116 GLP-1R Antagonist 1 Antagonist 99.84% Unkown
HY-153865 Lotiglipron Agonist 99.68% Unkown
HY-142162 LSN3318839 Modulator 99.81% Unkown
HY-143312 V-0219 Modulator 98.65% Unkown
HY-112679 GLP-1 receptor agonist 2 Agonist 98.70% Unkown
HY-141839 GLP-1R modulator C16 Modulator 99.60% Unkown
HY-116819A VU0453379 hydrochloride Modulator ≥99.0% Unkown
HY-141842 GLP-1R modulator L7-028 Modulator 98.77% Unkown
HY-143312A V-0219 hydrochloride Modulator 99.65% Unkown
HY-141840 GLP-1R modulator C5 Modulator 99.60% Unkown
HY-144035 GLP-1R agonist 4 Agonist 98.26% Unkown
HY-144034 GLP-1R agonist 3 Agonist 99.15% Unkown
HY-147625 GLP-1R agonist 12 Agonist 95.06% Unkown
HY-148212 GLP-1R agonist 17 Agonist 99.82% Unkown
HY-P10302A GLP-1R/GIPR agonist-1 (soduim) Agonist 96.55% Unkown
HY-112185A Orforglipron hemicalcium hydrate Agonist 99.48% Unkown
HY-116819 VU0453379 Modulator ≥98.0% Unkown
HY-143312E (S)-V-0219 hydrochloride Modulator 99.71% Unkown
HY-147623 GLP-1R agonist 10 Agonist 98.99% Unkown
HY-143312D (R)-V-0219 hydrochloride Modulator 99.37% Unkown
HY-147622 GLP-1R agonist 9 Agonist / Unkown
HY-P10302 GLP-1R/GIPR agonist-1 Agonist / Unkown
HY-P10716 Exendin-P5 Activator 96.70% Unkown
HY-138996 GLP-1 receptor agonist 8 Agonist / Unkown
HY-120828 Albenatide Agonist / Unkown
HY-129657 GLP-1 receptor agonist 4 Agonist / Unkown
HY-143312B (R)-V-0219 Modulator / Unkown
HY-143312C (S)-V-0219 Modulator / Unkown
HY-144033 GLP-1R agonist 1 Agonist / Unkown
HY-144133 GLP-1R agonist 5 Agonist / Unkown
HY-144134 GLP-1R agonist 6 Agonist / Unkown
HY-144135 GLP-1R agonist 7 Agonist / Unkown
HY-144136 GLP-1R agonist 8 Agonist / Unkown
HY-147626 GLP-1R agonist 13 Agonist / Unkown
HY-147627 GLP-1R agonist 14 Agonist / Unkown
HY-147628 GLP-1R agonist 15 Agonist / Unkown
HY-147629 GLP-1R agonist 16 Agonist / Unkown
HY-153193 LSN3160440 Modulator / Unkown
HY-160031 GLP-1R agonist 19 Agonist / Unkown
HY-161915 GLP-1R agonist 23 Agonist / Unkown
HY-162306 GLP-1R agonist 18 Agonist / Unkown
HY-162435 GLP-1R agonist 20 Agonist / Unkown
HY-162436 GLP-1R agonist 21 Agonist / Unkown
HY-162437 GLP-1R agonist 22 Agonist / Unkown
HY-162979 GLP-1R agonist 25 Agonist / Unkown
HY-163996 DD202-114 Agonist 98.47% Unkown
HY-P0264A Exendin(9-39) amide acetate Antagonist / Unkown
HY-P10337 OXM-7 Agonist / Unkown
HY-P3539 Exendin-4 (3-39) / Unkown
HY-P3542 Des His1, Glu8 Exendin-4 Antagonist / Unkown
HY-P4386 (Asp28)-Exenatide Agonist / Unkown
HY-P5161A FC382K10W15 TFA Agonist / Unkown
HY-RS05490 GLP1R Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-125824A Danuglipron tromethamine Agonist / Unkown
HY-142162A (S,R)-LSN3318839 / Unkown
HY-168585 GLP-1R agonist 26 Agonist / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990013 Gulgafafusp alfa Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Glp1r NCBI NCBI:2740