2. Gene
  3. Icam1 - intercellular adhesion molecule 1 Gene

Icam1 - intercellular adhesion molecule 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CD54; Ly-47; Icam-1; MALA-2

Gene ID: 15894 | Gene type: protein coding

About Icam1

Summary

This gene encodes an integral membrane protein that binds leukocyte adhesion protein LFA-1. It participates in the innate immune response. [provided by RefSeq, Aug 2016]

Icam1 Products(1)

mRNA Protein Name
NM_010493.3 NP_034623.1 intercellular adhesion molecule 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within T cell antigen processing and presentation IDA
IDA: Inferred from direct assay
2479693 MGI
acts upstream of or within T cell extravasation IMP
IMP: Inferred from mutant phenotype
17344467 MGI
acts upstream of or within cell adhesion IDA
IDA: Inferred from direct assay
10528208 MGI
acts upstream of or within cell adhesion mediated by integrin IDA
IDA: Inferred from direct assay
10601245 MGI
acts upstream of or within cellular response to glucose stimulus IDA
IDA: Inferred from direct assay
17670746 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
acts upstream of or within leukocyte cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
8562500 MGI
acts upstream of or within regulation of ruffle assembly IDA
IDA: Inferred from direct assay
23372835 MGI
Cellular Component GO Annotation Evidence Reference Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
16973387 MGI
located in immunological synapse IDA
IDA: Inferred from direct assay
14973438 MGI
colocalizes with membrane raft IDA
IDA: Inferred from direct assay
12763482 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

intercellular adhesion molecule 1

myD10

Recombinant Icam1 Proteins

Cat. No. Product Name Accession Purity
HY-P73112 ICAM-1/CD54 Protein, Mouse (HEK293, His-Fc) P13597 (Q28-N485) ≥95%
HY-P73113 ICAM-1/CD54 Protein, Mouse (HEK293, His) P13597 (Q28-N485) ≥95%

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-19344 Lifitegrast Antagonist 99.29% Unkown
HY-19344A Lifitegrast sodium Inhibitor 99.33% Unkown
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-145728 Alicaforsen Inhibitor / Phase 3
HY-145728A Alicaforsen sodium Inhibitor / Phase 3
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99473 Bersanlimab Inhibitor ≥99.0% Phase 2
Pre-clinical Phase
Bioactive Molecules (22)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100226 A-205804 Inhibitor 98.12% Unkown
HY-33037 Phenazine-1-carboxylic acid Inhibitor 99.88% Unkown
HY-15701 Leukadherin-1 Agonist ≥98.0% Unkown
HY-P1110 AF12198 Inhibitor 99.75% Unkown
HY-110117 BIRT 377 Inhibitor 98.07% Unkown
HY-N0602 Ginsenoside Rg2 Inhibitor 98.11% Unkown
HY-107587 A-286982 Inhibitor 99.33% Unkown
HY-U00003 ICAM-1-IN-1 Inhibitor 99.93% Unkown
HY-W588250 Surfactin C1 Antagonist 99.36% Unkown
HY-145728B (R/S)-Alicaforsen Inhibitor 97.08% Unkown
HY-P2508 MUC1, mucin core 99.85% Unkown
HY-10596 BMS-688521 Inhibitor 98.62% Unkown
HY-110086 RWJ 50271 Inhibitor 99.25% Unkown
HY-W013557 3-Hydroxyxanthone Inhibitor ≥98.0% Unkown
HY-13412 Cariporide (mesilate) Modulator / Unkown
HY-101961 Tyrphostin AG 1288 Inhibitor 98.68% Unkown
HY-143243 Antioxidant agent-5 Inhibitor / Unkown
HY-N0602R Ginsenoside Rg2 (Standard) Inhibitor / Unkown
HY-N11996 Aloenin aglycone / Unkown
HY-N4275 Oleaside A / Unkown
HY-RS06512 ICAM1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-122192 ICAM-1988 / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99336 Enlimomab Inhibitor 95.00% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Icam1 NCBI NCBI:3383
Canis familiaris Icam1 NCBI NCBI:403975
Macaca mulatta Icam1 NCBI NCBI:712280