2. Gene
  3. Cxcl10 - chemokine (C-X-C motif) ligand 10 Gene

Cxcl10 - chemokine (C-X-C motif) ligand 10 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10

Gene ID: 15945 | Gene type: protein coding

About Cxcl10

Summary

Predicted to enable chemoattractant activity; Chemokine Receptor binding activity; and heparin binding activity. Acts upstream of or within several processes, including defense response to virus; negative regulation of myoblast differentiation; and negative regulation of myoblast fusion. Located in external side of plasma membrane and extracellular space. Is expressed in several structures, including alimentary system; axial skeleton; hemolymphoid system; and liver. Human ortholog(s) of this gene implicated in hepatitis B; middle cerebral artery infarction; and type 1 diabetes mellitus. Orthologous to human CXCL10 (C-X-C motif chemokine ligand 10). [provided by Alliance of Genome Resources, Apr 2022]

Cxcl10 Products(1)

mRNA Protein Name
NM_021274.2 NP_067249.1 C-X-C motif chemokine 10 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to interleukin-17 IDA
IDA: Inferred from direct assay
30294880 MGI
acts upstream of or within defense response to virus IDA
IDA: Inferred from direct assay
17277142 MGI
acts upstream of or within negative regulation of myoblast differentiation IMP
IMP: Inferred from mutant phenotype
23844157 MGI
acts upstream of or within negative regulation of myoblast fusion IMP
IMP: Inferred from mutant phenotype
23844157 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
Cellular Component GO Annotation Evidence Reference Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
19008373 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
11894098 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-X-C motif chemokine 10

10 kDa interferon gamma-induced protein

gamma-IP10

interferon activated gene 10

interferon-gamma induced protein CRG-2

small inducible cytokine B subfamily (Cys-X-Cys), member 10

small-inducible cytokine B10

Recombinant Cxcl10 Proteins

Cat. No. Product Name Accession Purity
HY-P7227 IP-10/CRG-2/CXCL10 Protein, Mouse P17515 (I22-P98) ≥95%
HY-P700168AF Animal-Free IP-10/CRG-2/CXCL10 Protein, Mouse (His) P17515 (I22-P98) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99190 Eldelumab Inhibitor 95.00% Phase 2
Pre-clinical Phase
Bioactive Molecules (19)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15319 AMG 487 Inhibitor 99.65% Unkown
HY-15589 GW9508 99.33% Unkown
HY-15320 NBI-74330 Antagonist 98.57% Unkown
HY-152237 TBK1-IN-1 Inhibitor 99.91% Unkown
HY-111149A PS372424 hydrochloride Agonist ≥98.0% Unkown
HY-152956 STING agonist-23 Agonist 99.16% Unkown
HY-124151 Adenosine-2'-monophosphate Activator 99.91% Unkown
HY-122891 SB02024 99.7% Unkown
HY-152959 STING agonist-26 Agonist 99.56% Unkown
HY-111149 PS372424 Agonist / Unkown
HY-RS03384 CXCL10 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-152957 STING agonist-24 Agonist / Unkown
HY-152958 STING agonist-25 Agonist / Unkown
HY-152961 STING agonist-28 Agonist / Unkown
HY-15319A (±)-AMG 487 Inhibitor / Unkown
HY-162675 COB-187 Inhibitor / Unkown
HY-W104821 Rosolic acid Activator / Unkown
HY-113730 VUF5834 / Unkown
HY-167884 PF-1367550 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cxcl10 NCBI NCBI:3627
Susscrofa domestica Cxcl10 NCBI
Rattus norvegicus Cxcl10 NCBI NCBI:245920
Macaca mulatta Cxcl10 NCBI NCBI:574243