2. Gene
  3. PPTC7 - protein phosphatase targeting COQ7 Gene

PPTC7 - protein phosphatase targeting COQ7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as TAPP2C; TA-PP2C

Gene ID: 160760 | Gene type: protein coding

About PPTC7

Cytogenetic location: 12q24.11 Genomic coordinates (GRCh38): 12:110,533,245-110,583,318 (from NCBI)

This gene has 2 transcripts (splice variants) and 278 orthologues. Ubiquitous expression in bone marrow (RPKM 18.8), heart (RPKM 15.4) and 25 other tissues.

Summary

Enables protein serine/threonine Phosphatase activity. Involved in peptidyl-serine dephosphorylation and regulation of ubiquinone biosynthetic process. Located in mitochondrial matrix. [provided by Alliance of Genome Resources, Apr 2022]

PPTC7 Products(1)

mRNA Protein Name
NM_139283.2 NP_644812.1 protein phosphatase PTC7 homolog
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
27499296 GOA
enables protein serine/threonine phosphatase activity IMP
IMP: Inferred from mutant phenotype
30267671 GOA
Biological Process GO Annotation Evidence Reference Source
involved in peptidyl-serine dephosphorylation IMP
IMP: Inferred from mutant phenotype
30267671 GOA
involved in regulation of ubiquinone biosynthetic process IMP
IMP: Inferred from mutant phenotype
30267671 GOA
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrial matrix IMP
IMP: Inferred from mutant phenotype
30267671 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PPTC7 Protein Structure

SpoIIE

SpoIIE: Stage II sporulation protein E (SpoIIE) (74 - 296)

  • 0
  • 100
  • 200
  • 304 a.a.
Protein Preferred Names Protein Names

protein phosphatase PTC7 homolog

PTC7 protein phosphatase homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11040 PPTC7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris PPTC7 VGNC VGNC:44931
Felis catus PPTC7 VGNC VGNC:64336
Mus musculus PPTC7 MGD MGI:2444593
Bos taurus PPTC7 VGNC VGNC:33278
Rattus norvegicus PPTC7 RGD RGD:1310383