2. Gene
  3. BNIP3 - BCL2 interacting protein 3 Gene

BNIP3 - BCL2 interacting protein 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as NIP3; HABON

Gene ID: 664 | Gene type: protein coding

About BNIP3

Cytogenetic location: 10q26.3 Genomic coordinates (GRCh38): 10:131,967,684-131,981,923 (from NCBI)

This gene has 4 transcripts (splice variants), 221 orthologues and 1 paralogue. Ubiquitous expression in liver (RPKM 54.5), fat (RPKM 52.6) and 24 other tissues.

Summary

This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014]

BNIP3 Products(1)

mRNA Protein Name
NM_004052.4 NP_004043.4 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables GTPase binding IPI
IPI: Inferred from physical interaction
20436456 GOA
enables endoplasmic reticulum-autophagosome adaptor activity IDA
IDA: Inferred from direct assay
22505714 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
10381623 GOA
enables mitochondrion autophagosome adaptor activity IDA
IDA: Inferred from direct assay
22505714 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
7954800 GOA
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
9396766 GOA
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to cobalt ion IMP
IMP: Inferred from mutant phenotype
20436456 GOA
acts upstream of or within cellular response to hypoxia IGI
IGI: Inferred from genetic interaction
19273585 GOA
involved in cellular response to hypoxia IMP
IMP: Inferred from mutant phenotype
20436456 GOA
involved in defense response to virus IDA
IDA: Inferred from direct assay
9973195 GOA
involved in granzyme-mediated programmed cell death signaling pathway IDA
IDA: Inferred from direct assay
9396766 GOA
involved in intrinsic apoptotic signaling pathway in response to hypoxia IMP
IMP: Inferred from mutant phenotype
20436456 GOA
involved in mitochondrial fragmentation involved in apoptotic process IDA
IDA: Inferred from direct assay
20436456 GOA
involved in mitochondrial outer membrane permeabilization IDA
IDA: Inferred from direct assay
18371312 GOA
involved in mitochondrial protein catabolic process IMP
IMP: Inferred from mutant phenotype
22292033 GOA
involved in mitophagy IMP
IMP: Inferred from mutant phenotype
22505714 GOA
involved in negative regulation of membrane potential IDA
IDA: Inferred from direct assay
10891486 GOA
involved in negative regulation of mitochondrial fusion IDA
IDA: Inferred from direct assay
20436456 GOA
acts upstream of or within negative regulation of programmed cell death IGI
IGI: Inferred from genetic interaction
19273585 GOA
involved in positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
9973195 GOA
acts upstream of or within positive regulation of macroautophagy IGI
IGI: Inferred from genetic interaction
19273585 GOA
involved in positive regulation of mitochondrial fission IDA
IDA: Inferred from direct assay
20436456 GOA
involved in positive regulation of programmed cell death IDA
IDA: Inferred from direct assay
10891486 GOA
involved in positive regulation of protein-containing complex disassembly IDA
IDA: Inferred from direct assay
20436456 GOA
involved in positive regulation of release of cytochrome c from mitochondria IDA
IDA: Inferred from direct assay
20436456 GOA
involved in reactive oxygen species metabolic process IDA
IDA: Inferred from direct assay
10891486 GOA
involved in regulation of mitochondrial membrane permeability IDA
IDA: Inferred from direct assay
10891486 GOA
involved in reticulophagy IMP
IMP: Inferred from mutant phenotype
22505714 GOA
Cellular Component GO Annotation Evidence Reference Source
is active in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
22505714 GOA
located in mitochondrial membrane IDA
IDA: Inferred from direct assay
10891486 GOA
located in mitochondrial membrane IMP
IMP: Inferred from mutant phenotype
9396766 GOA
is active in mitochondrial outer membrane IDA
IDA: Inferred from direct assay
22505714 GOA
located in mitochondrial outer membrane IDA
IDA: Inferred from direct assay
10891486 GOA
located in mitochondrion IDA
IDA: Inferred from direct assay
7954800 GOA
located in nuclear envelope IDA
IDA: Inferred from direct assay
7954800 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BNIP3 Protein Structure

BNIP3

BNIP3: BNIP3 (1 - 192)

  • 0
  • 100
  • 194 a.a.
Protein Preferred Names Protein Names

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

BCL2/adenovirus E1B 19kDa interacting protein 3

BNIP3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra BNIP3 Q12983 LDLRAD1 Homo sapiens Q5T700
Validated Y2H
32296183
Intra BNIP3 Q12983 LDLRAD1 Homo sapiens Q5T700
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 LDLRAD1 Homo sapiens Q5T700
Y2H Prey Pooling
25416956
Intra BNIP3 Q12983 LDLRAD1 Homo sapiens Q5T700
Y2H Array
32296183
Intra BNIP3 Q12983 LDLRAD1 Homo sapiens Q5T700
Y2H Array
25416956
Intra BNIP3 Q12983 JAGN1 Homo sapiens Q8N5M9
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 JAGN1 Homo sapiens Q8N5M9
Validated Y2H
32296183
Intra BNIP3 Q12983 JAGN1 Homo sapiens Q8N5M9
Y2H Array
32296183
Intra BNIP3 Q12983 RPRM Homo sapiens Q9NS64
Validated Y2H
32296183
Intra BNIP3 Q12983 OPA1 Homo sapiens O60313
Y2H
20436456
Intra BNIP3 Q12983 OPA1 Homo sapiens O60313
Pull Down
20436456
Intra BNIP3 Q12983 OPA1 Homo sapiens O60313
Anti Tag CoIP
20436456
Intra BNIP3 Q12983 OPA1 Homo sapiens O60313
Anti Bait CoIP
20436456
Intra BNIP3 Q12983 REEP2 Homo sapiens Q9BRK0
Validated Y2H
32296183
Intra BNIP3 Q12983 REEP2 Homo sapiens Q9BRK0
Y2H Array
32296183
Intra BNIP3 Q12983 REEP2 Homo sapiens Q9BRK0
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 ARL13B Homo sapiens Q3SXY8
Validated Y2H
32296183
Intra BNIP3 Q12983 ARL13B Homo sapiens Q3SXY8
Y2H Array
32296183
Intra BNIP3 Q12983 ARL13B Homo sapiens Q3SXY8
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 CMTM5 Homo sapiens Q96DZ9-2
Validated Y2H
32296183
Intra BNIP3 Q12983 CLEC7A Homo sapiens Q9BXN2-6
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 CLEC7A Homo sapiens Q9BXN2-6
Y2H Array
32296183
Intra BNIP3 Q12983 CLEC7A Homo sapiens Q9BXN2-6
Validated Y2H
32296183
Intra BNIP3 Q12983 TNMD Homo sapiens Q9H2S6-2
Validated Y2H
32296183
Intra BNIP3 Q12983 KTN1 Homo sapiens Q86UP2-3
Validated Y2H
32296183
Intra BNIP3 Q12983 CD3E Homo sapiens P07766
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 CD3E Homo sapiens P07766
Y2H Array
32296183
Intra BNIP3 Q12983 FAM241B Homo sapiens Q96D05-2
Validated Y2H
32296183
Intra BNIP3 Q12983 SLC35B1 Homo sapiens P78383
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 SLC35B1 Homo sapiens P78383
Y2H Array
32296183
Intra BNIP3 Q12983 TMPRSS2 Homo sapiens O15393-2
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 TMPRSS2 Homo sapiens O15393-2
Y2H Array
32296183
Intra BNIP3 Q12983 MS4A3 Homo sapiens Q96HJ5
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 MS4A3 Homo sapiens Q96HJ5
Y2H Array
32296183
Intra BNIP3 Q12983 MS4A3 Homo sapiens Q96HJ5
Validated Y2H
32296183
Intra BNIP3 Q12983 HPN Homo sapiens P05981
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 HPN Homo sapiens P05981
Y2H Array
32296183
Intra BNIP3 Q12983 ZDHHC15 Homo sapiens Q96MV8
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 ZDHHC15 Homo sapiens Q96MV8
Y2H Array
32296183
Intra BNIP3 Q12983 ZDHHC15 Homo sapiens Q96MV8
Validated Y2H
32296183
Intra BNIP3 Q12983 TLCD4 Homo sapiens Q96MV1
Validated Y2H
32296183
Intra BNIP3 Q12983 TLCD4 Homo sapiens Q96MV1
Y2H Array
32296183
Intra BNIP3 Q12983 TLCD4 Homo sapiens Q96MV1
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 RNF24 Homo sapiens Q9Y225-2
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 RNF24 Homo sapiens Q9Y225-2
Validated Y2H
32296183
Intra BNIP3 Q12983 RNF24 Homo sapiens Q9Y225-2
Y2H Array
32296183
Intra BNIP3 Q12983 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 GPR152 Homo sapiens Q8TDT2
Validated Y2H
32296183
Intra BNIP3 Q12983 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
Intra BNIP3 Q12983 TM4SF18 Homo sapiens Q96CE8
Validated Y2H
32296183
Intra BNIP3 Q12983 TM4SF18 Homo sapiens Q96CE8
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 TM4SF18 Homo sapiens Q96CE8
Y2H Array
32296183
Intra BNIP3 Q12983 SCN3B Homo sapiens Q9NY72
Y2H Array
32296183
Intra BNIP3 Q12983 SCN3B Homo sapiens Q9NY72
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 SCN3B Homo sapiens Q9NY72
Validated Y2H
32296183
Intra BNIP3 Q12983 SPACA1 Homo sapiens Q9HBV2
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 SPACA1 Homo sapiens Q9HBV2
Validated Y2H
32296183
Intra BNIP3 Q12983 SPACA1 Homo sapiens Q9HBV2
Y2H Array
32296183
Intra BNIP3 Q12983 SLC31A2 Homo sapiens O15432
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 SLC31A2 Homo sapiens O15432
Y2H Array
32296183
Intra BNIP3 Q12983 GPR42 Homo sapiens O15529
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 GPR42 Homo sapiens O15529
Y2H Array
32296183
Intra BNIP3 Q12983 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 FAM209A Homo sapiens Q5JX71
Validated Y2H
32296183
Intra BNIP3 Q12983 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Intra BNIP3 Q12983 CLDN9 Homo sapiens O95484
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 CLDN9 Homo sapiens O95484
Y2H Array
32296183
Intra BNIP3 Q12983 SLC6A17 Homo sapiens Q9H1V8
Validated Y2H
32296183
Intra BNIP3 Q12983 SLC6A17 Homo sapiens Q9H1V8
Y2H Array
32296183
Intra BNIP3 Q12983 SLC6A17 Homo sapiens Q9H1V8
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 RNASEK Homo sapiens Q6P5S7
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 RNASEK Homo sapiens Q6P5S7
Validated Y2H
32296183
Intra BNIP3 Q12983 RNASEK Homo sapiens Q6P5S7
Y2H Array
32296183
Intra BNIP3 Q12983 ELOVL4 Homo sapiens Q9GZR5
Validated Y2H
32296183
Intra BNIP3 Q12983 ELOVL4 Homo sapiens Q9GZR5
Y2H Array
32296183
Intra BNIP3 Q12983 ELOVL4 Homo sapiens Q9GZR5
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 AMIGO1 Homo sapiens Q86WK6
Validated Y2H
32296183
Intra BNIP3 Q12983 AMIGO1 Homo sapiens Q86WK6
Y2H Array
32296183
Intra BNIP3 Q12983 AMIGO1 Homo sapiens Q86WK6
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 TMEM106C Homo sapiens Q9BVX2
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 TMEM106C Homo sapiens Q9BVX2
Y2H Array
32296183
Intra BNIP3 Q12983 TMEM106C Homo sapiens Q9BVX2
Validated Y2H
32296183
Intra BNIP3 Q12983 FFAR2 Homo sapiens O15552
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 FFAR2 Homo sapiens O15552
Y2H Array
32296183
Intra BNIP3 Q12983 FAM3C Homo sapiens Q92520
Validated Y2H
32296183
Intra BNIP3 Q12983 KTN1 Homo sapiens Q86UP2
Y2H Prey Pooling
25416956
Intra BNIP3 Q12983 KTN1 Homo sapiens Q86UP2
Validated Y2H
25416956
Intra BNIP3 Q12983 KTN1 Homo sapiens Q86UP2
Y2H Array
25416956
Intra BNIP3 Q12983 MFSD14B Homo sapiens Q5SR56
Validated Y2H
32296183
Intra BNIP3 Q12983 MFSD14B Homo sapiens Q5SR56
Y2H Array
32296183
Intra BNIP3 Q12983 MFSD14B Homo sapiens Q5SR56
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 IFNGR2 Homo sapiens P38484
Y2H Array
32296183
Intra BNIP3 Q12983 IFNGR2 Homo sapiens P38484
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 EBP Homo sapiens Q15125
Validated Y2H
32296183
Intra BNIP3 Q12983 EBP Homo sapiens Q15125
Y2H Array
32296183
Intra BNIP3 Q12983 TMEM101 Homo sapiens Q96IK0
Validated Y2H
32296183
Intra BNIP3 Q12983 TMEM101 Homo sapiens Q96IK0
Y2H Array
32296183
Intra BNIP3 Q12983 TMEM205 Homo sapiens Q6UW68
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 TMEM205 Homo sapiens Q6UW68
Validated Y2H
32296183
Intra BNIP3 Q12983 TMEM205 Homo sapiens Q6UW68
Y2H Array
32296183
Intra BNIP3 Q12983 TMX2 Homo sapiens Q9Y320
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 TMX2 Homo sapiens Q9Y320
Y2H Array
32296183
Intra BNIP3 Q12983 TMX2 Homo sapiens Q9Y320
Validated Y2H
32296183
Intra BNIP3 Q12983 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 CREB3L1 Homo sapiens Q96BA8
Validated Y2H
32296183
Intra BNIP3 Q12983 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra BNIP3 Q12983 BIK Homo sapiens Q13323
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 BIK Homo sapiens Q13323
Y2H Array
32296183
Intra BNIP3 Q12983 BIK Homo sapiens Q13323
Validated Y2H
32296183
Intra BNIP3 Q12983 TMEM11 Homo sapiens P17152
Validated Y2H
27107012
Intra BNIP3 Q12983 TMEM11 Homo sapiens P17152
Y2H Pooling
16189514
Intra BNIP3 Q12983 TMEM11 Homo sapiens P17152
Anti Tag CoIP
33961781
Intra BNIP3 Q12983 TMEM11 Homo sapiens P17152
Anti Tag CoIP
28514442
Intra BNIP3 Q12983 TMEM11 Homo sapiens P17152
Y2H Prey Pooling
25416956
Intra BNIP3 Q12983 TMEM11 Homo sapiens P17152
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 TMEM11 Homo sapiens P17152
Y2H Array
32296183
Intra BNIP3 Q12983 SMIM3 Homo sapiens Q9BZL3
Validated Y2H
32296183
Intra BNIP3 Q12983 SMIM3 Homo sapiens Q9BZL3
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 SMIM3 Homo sapiens Q9BZL3
Y2H Array
32296183
Intra BNIP3 Q12983 FATE1 Homo sapiens Q969F0
Validated Y2H
25416956
Intra BNIP3 Q12983 FATE1 Homo sapiens Q969F0
Validated Y2H
32296183
Intra BNIP3 Q12983 FATE1 Homo sapiens Q969F0
Y2H Array
25416956
Intra BNIP3 Q12983 FATE1 Homo sapiens Q969F0
Y2H Array
32296183
Intra BNIP3 Q12983 FATE1 Homo sapiens Q969F0
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 BNIP3L Homo sapiens O60238
Validated Y2H
25416956
Intra BNIP3 Q12983 BNIP3L Homo sapiens O60238
Anti Tag CoIP
33961781
Intra BNIP3 Q12983 BNIP3L Homo sapiens O60238
Anti Tag CoIP
28514442
Intra BNIP3 Q12983 BNIP3L Homo sapiens O60238
Y2H Array
25416956
Intra BNIP3 Q12983 BNIP3L Homo sapiens O60238
Y2H
10381623
Intra BNIP3 Q12983 BNIP3L Homo sapiens O60238
SLC
27107012
Intra BNIP3 Q12983 BNIP3L Homo sapiens O60238
BFG-2H
27107012
Intra BNIP3 Q12983 BNIP3L Homo sapiens O60238
Y2H
21516116
Intra BNIP3 Q12983 BNIP3L Homo sapiens O60238
Y2H Pooling
16189514
Intra BNIP3 Q12983 BNIP3L Homo sapiens O60238
Validated Y2H
27107012
Intra BNIP3 Q12983 MALL Homo sapiens Q13021
Validated Y2H
32296183
Intra BNIP3 Q12983 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
Intra BNIP3 Q12983 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
Intra BNIP3 Q12983 SEC23A Homo sapiens Q15436
Validated Y2H
32296183
Intra BNIP3 Q12983 SEC22A Homo sapiens Q96IW7
Validated Y2H
32296183
Intra BNIP3 Q12983 EBAG9 Homo sapiens O00559
Y2H Prey Pooling
32296183
Intra BNIP3 Q12983 EBAG9 Homo sapiens O00559
Y2H Array
32296183
Intra BNIP3 Q12983 PPTC7 Homo sapiens Q8NI37
Y2H Array
32296183
Intra BNIP3 Q12983 PPTC7 Homo sapiens Q8NI37
Validated Y2H
32296183
Intra BNIP3 Q12983 PPTC7 Homo sapiens Q8NI37
Anti Tag CoIP
33961781
Intra BNIP3 Q12983 PPTC7 Homo sapiens Q8NI37
Anti Tag CoIP
28514442
Intra BNIP3 Q12983 PPTC7 Homo sapiens Q8NI37
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant BNIP3 Proteins

Cat. No. Product Name Accession Purity
HY-P7670 BNIP3/NIP3 Protein, Human (His) AAH21989.1 (M1-L166) ≥95%

Related Diseases

Diseases Alias
Hereditary Leiomyomatosis And Renal Cell Cancer

HLRCC

Lrcc

Mcl

Multiple Cutaneous And Uterine Leiomyomata

Leiomyomatosis And Renal Cell Cancer

Mcul

Mcul1

Familial Leiomyomatosis And Renal Cell Cancer

Familial Leiomyomatosis Cutis Et Uteri

Familial Leiomyomatosis With Renal Carcinoma

Familial Multiple Cutaneous Leiomyomas

Reed'S Syndrome

Multiple Cutaneous And Uterine Leiomyomata 1, With Or Without Renal Cell Carcinoma

Leiomyomatosis And Renal Cell Cancer, Hereditary

Leiomyoma, Multiple Cutaneous

Multiple Cutaneous Leiomyomata

Hereditary Leiomyomatosis And Renal Cell Carcinoma

Multiple Cutaneous Leiomyoma

Hereditary Leiomyomatosis

Hereditary Leiomyomatosis With Renal Carcinoma

Hereditary Multiple Cutaneous Leiomyomas

Multiple Cutaneous And Uterine Leiomyomas

Reed Syndrome

Leiomyoma Multiple Cutaneous

Leiomyomatosis And Renal Cell Cancer Hereditary

Multiple Cutaneous And Uterine Leiomyomata 1 With Or Without Renal Cell Carcinoma
Leiomyomatosis
Pancreatic Cancer

Pancreatic Carcinoma

Carcinoma Of Pancreas

Familial Pancreatic Carcinoma

Pancreatic Neoplasm

Pancreatic Carcinoma, Familial

Malignant Neoplasm Of Pancreas

Pancreatic Acinar Carcinoma

Pancreatic Tumor

Familial Pancreatic Cancer

Neoplasm Of The Pancreas

Cancer Of The Pancreas

Pancreatic Carcinoma, Somatic

Pancreatic Cancer, Somatic

Ca Body Of Pancreas

Ca Head Of Pancreas

Ca Tail Of Pancreas

Malignant Neoplasm Of Body Of Pancreas

Malignant Neoplasm Of Head Of Pancreas

Malignant Neoplasm Of Tail Of Pancreas

Pancreas Neoplasm

Exocrine Cancer

Exocrine Pancreas Carcinoma

Hereditary Pancreatic Cancer

Hereditary Pancreatic Carcinoma

PNCA

Pancreatic Cancer, Susceptibility To

Carcinoma Of Head Of Pancreas

Pancreatic Neoplasms

Pancreatic Tumors

Cancer, Pancreatic

Cancer Of Pancreas

Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Follicular Lymphoma

Lymphoma, Follicular

Lymphoma Follicular

Brill-Symmers' Disease

Large Cell Follicular Non-Hodgkin Lymphoma

Diffuse Follicle Centre Lymphoma

Diffuse Follicular Lymphoma Nos

Follicular Nodular Non-Hodgkin Lymphoma, Unspecified

Follicular Large Cell Cleaved Or Noncleaved Lymphoma

Large Cell Follicular Noncleaved Lymphoma

Follicular Lymphoma With Or Without Diffuse Areas

Histiocytic Follicular Lymphoma

Histiocytic Nodular Lymphoma

Histiocytic Nodular Malignant Lymphoma

Large Cell Follicular Lymphoma

Large Cell Noncleaved Follicular Lymphoma

Large Cell Noncleaved Follicular Malignant Lymphoma

Nodular Reticulum Cell Sarcoma

Noncleaved Follicular Lymphoma
Adrenal Gland Pheochromocytoma

Pheochromocytoma
Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon
High Grade Glioma

Malignant Glioma

Glial Cell Tumor

Glioma, Malignant

Malignant Neuroglial Tumor

Neuroglial Tumor

Glioma

Malignant Gliomas
Bone Cancer

Malignant Bone Neoplasm

Bone Carcinoma

Bone Neoplasms

Bone Neoplasm

Bone Tumour

Ca - Bone Cancer

Malignant Bone Tumour

Malignant Neoplasm Of Bone

Malignant Osseous Tumor

Neoplasm Of Bone

Osseous Tumor

Osteosarcoma Of Bone

Osteogenic Neoplasm
Pheochromocytoma

Pheochromocytoma, Susceptibility To

Phaeochromocytoma

Adrenal Gland Chromaffin Paraganglioma

Adrenal Gland Chromaffinoma

Adrenal Gland Paraganglioma

Adrenal Gland Pheochromocytoma

Chromaffin Paraganglioma Of The Adrenal Gland

Intraadrenal Paraganglioma

PCC

Chromaffin Cell Tumor

Medullary Chromaffinoma

Medullary Paraganglioma

Pheochromoblastoma

Pheochromocytomas

Chromaffin Cell Neoplasm

Pheochromocytoma, Malignant
Ichthyosis, Congenital, Autosomal Recessive 3

Autosomal Recessive Congenital Ichthyosis 3

ARCI3

Lamellar Ichthyosis 5

Collodion Baby, Self-Healing

Ichthyosis, Lamellar, 5, Formerly

Li5, Formerly

Li5

Self-Healing Collodion Baby

Ichthyosis, Congenital, Autosomal Recessive, Type 3
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer
Dilated Cardiomyopathy

Familial Dilated Cardiomyopathy

Primary Dilated Cardiomyopathy

Idiopathic Dilated Cardiomyopathy

Congestive Cardiomyopathy

Idiopathic Dilation Cardiomyopathy

Primary Familial Dilated Cardiomyopathy

Cardiomyopathy, Dilated

DCM

Cardiomyopathy, Familial Dilated

Dilated Cardiomyopathy, Familial

Hypokinetic Dilated Cardiomyopathy, Familial

Familial Idiopathic Cardiomyopathy

Fdc

Cardiomyopathy, Familial Idiopathic

Idiopathic Cardiomegaly

Dilated Congestive Cardiomyopathy

Chronic Dilated Cardiomyopathy

Ccm - [Congestive Cardiomyopathy]

Cocm - [Congestive Cardiomyopathy]

Dcm - [Dilated Cardiomyopathy]

Dilated-Hypokinetic Cardiomyopathy

Congestive Idiopathic Cardiomyopathy

Primary Idiopathic Dilated Cardiomyopathy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-158341 IOX5 99.39% Unkown
HY-121859 RU28362 Agonist / Unkown
HY-RS01564 BNIP3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS01565 BNIP3L Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta BNIP3 VGNC VGNC:70273
Rattus norvegicus BNIP3 RGD RGD:620800
Canis familiaris BNIP3 VGNC VGNC:38493
Mus musculus BNIP3 MGD MGI:109326
Bos taurus BNIP3 VGNC VGNC:26533
Others BNIP3 NCBI