CDC20B - cell division cycle 20B Gene

Homo sapiens

Also known as G6VTS76519

Gene ID: 166979 | Gene type: protein coding

About CDC20B

This gene has 5 transcripts (splice variants), 121 orthologues and 2 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable anaphase-promoting complex binding activity and ubiquitin Ligase activator activity. Predicted to be involved in anaphase-promoting complex-dependent catabolic process and positive regulation of anaphase-promoting complex-dependent catabolic process. Predicted to be part of anaphase-promoting complex. [provided by Alliance of Genome Resources, Apr 2022]

CDC20B Products(3)

mRNA	Protein	Name
NM_001145734.2	NP_001139206.2	cell division cycle protein 20 homolog B isoform 2
NM_001170402.1	NP_001163873.1	cell division cycle protein 20 homolog B isoform 3
NM_152623.2	NP_689836.2	cell division cycle protein 20 homolog B isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in de novo centriole assembly	IDA IDA: Inferred from direct assay	30405130	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in deuterosome	IDA IDA: Inferred from direct assay	30405130	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CDC20B Protein Structure

WD40

0
100
200
300
400
519 a.a.

Protein Preferred Names

Protein Names

cell division cycle protein 20 homolog B

CDC20 cell division cycle 20 homolog B

CDC20B Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CDC20B	Q86Y33	KRT40	Homo sapiens	Q6A162	Validated Y2H	25416956
Intra	CDC20B	Q86Y33	KRT40	Homo sapiens	Q6A162	Y2H Array	25416956
Intra	CDC20B	Q86Y33	MAGEA11	Homo sapiens	P43364-2	Y2H Array	25416956
Intra	CDC20B	Q86Y33	CCDC57	Homo sapiens	Q2TAC2	Y2H Prey Pooling	25416956
Intra	CDC20B	Q86Y33	CCDC57	Homo sapiens	Q2TAC2	Validated Y2H	25416956
Intra	CDC20B	Q86Y33	CCDC57	Homo sapiens	Q2TAC2	Y2H Array	25416956
Intra	CDC20B	Q86Y33	TRAF2	Homo sapiens	Q12933	Validated Y2H	25416956
Intra	CDC20B	Q86Y33	TRAF2	Homo sapiens	Q12933	Y2H Array	25416956
Intra	CDC20B	Q86Y33	SPAG5	Homo sapiens	Q96R06	Validated Y2H	25416956
Intra	CDC20B	Q86Y33	GOLGA2	Homo sapiens	Q08379	Y2H Array	25416956
Intra	CDC20B	Q86Y33	GOLGA2	Homo sapiens	Q08379	Validated Y2H	25416956
Intra	CDC20B	Q86Y33	TRIM27	Homo sapiens	P14373	Y2H Array	25416956
Intra	CDC20B	Q86Y33	TRIM27	Homo sapiens	P14373	Validated Y2H	25416956
Intra	CDC20B	Q86Y33	PLK2	Homo sapiens	Q9NYY3	Validated Y2H	25416956
Intra	CDC20B	Q86Y33	PLK2	Homo sapiens	Q9NYY3	Y2H Array	25416956
Intra	CDC20B	Q86Y33	PLK2	Homo sapiens	Q9NYY3	Y2H Prey Pooling	25416956
Intra	CDC20B	Q86Y33	TRIM23	Homo sapiens	P36406	Y2H Prey Pooling	25416956
Intra	CDC20B	Q86Y33	TRIM23	Homo sapiens	P36406	Y2H Array	25416956
Intra	CDC20B	Q86Y33	TRIM37	Homo sapiens	O94972	Y2H Array	25416956
Intra	CDC20B	Q86Y33	TRIM37	Homo sapiens	O94972	Y2H Prey Pooling	25416956
Intra	CDC20B	Q86Y33	MTUS2	Homo sapiens	Q5JR59	Y2H Prey Pooling	25416956
Intra	CDC20B	Q86Y33	MTUS2	Homo sapiens	Q5JR59	Validated Y2H	25416956
Intra	CDC20B	Q86Y33	KRT31	Homo sapiens	Q15323	Validated Y2H	25416956
Intra	CDC20B	Q86Y33	KRT31	Homo sapiens	Q15323	Y2H Array	25416956
Intra	CDC20B	Q86Y33	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02289	CDC20B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	CDC20B	VGNC	VGNC:70843
Felis catus	CDC20B	VGNC	VGNC:102177
Bos taurus	CDC20B	VGNC	VGNC:27061
Mus musculus	CDC20B	MGD	MGI:3644472
Canis familiaris	CDC20B	VGNC	VGNC:38988
Rattus norvegicus	CDC20B	RGD	RGD:1584143

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