2. Gene
  3. CCDC57 - coiled-coil domain containing 57 Gene

CCDC57 - coiled-coil domain containing 57 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 284001 | Gene type: protein coding

About CCDC57

This gene has 21 transcripts (splice variants), 133 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 2.8), duodenum (RPKM 2.0) and 25 other tissues.

Summary

Involved in several processes, including G2/M transition of mitotic cell cycle; cilium assembly; and microtubule Cytoskeleton organization. Located in centriolar satellite; centriole; and spindle microtubule. [provided by Alliance of Genome Resources, Apr 2022]

CCDC57 Products(5)

mRNA Protein Name
NM_001316321.3 NP_001303250.1 coiled-coil domain-containing protein 57 isoform 2
NM_001367828.2 NP_001354757.1 coiled-coil domain-containing protein 57 isoform 3
NM_001394669.1 NP_001381598.1 coiled-coil domain-containing protein 57 isoform 4
NM_001394670.1 NP_001381599.1 coiled-coil domain-containing protein 57 isoform 4
NM_198082.4 NP_932348.2 coiled-coil domain-containing protein 57 isoform 1
Protein Preferred Names Protein Names

coiled-coil domain-containing protein 57

CCDC57 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra CCDC57 Q2TAC2 CEP57L1 Homo sapiens Q8IYX8-2
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 CEP57L1 Homo sapiens Q8IYX8-2
Y2H Array
25416956
Intra CCDC57 Q2TAC2 UTP14C Homo sapiens Q08E77
Y2H Array
25416956
Intra CCDC57 Q2TAC2 UTP14C Homo sapiens Q08E77
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 TSGA10IP Homo sapiens Q3SY00
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 LINC00526 Homo sapiens Q96FQ7
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 LINC00526 Homo sapiens Q96FQ7
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 LINC00526 Homo sapiens Q96FQ7
Y2H Array
25416956
Intra CCDC57 Q2TAC2 ROBO3 Homo sapiens Q96HH0
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 ROBO3 Homo sapiens Q96HH0
Y2H Array
25416956
Intra CCDC57 Q2TAC2 USP15 Homo sapiens Q9Y4E8
Y2H Array
25416956
Intra CCDC57 Q2TAC2 MFAP1 Homo sapiens P55081
Y2H Array
25416956
Intra CCDC57 Q2TAC2 PRPF31 Homo sapiens Q8WWY3
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 PTPN7 Homo sapiens P35236
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 PTPN7 Homo sapiens P35236
Y2H Array
25416956
Intra CCDC57 Q2TAC2 HAUS1 Homo sapiens Q96CS2
Y2H Array
25416956
Intra CCDC57 Q2TAC2 HAUS1 Homo sapiens Q96CS2
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 PPP1R18 Homo sapiens Q6NYC8
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 ZMAT2 Homo sapiens Q96NC0
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 PRR3 Homo sapiens P79522
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 PRR3 Homo sapiens P79522
Y2H Array
25416956
Intra CCDC57 Q2TAC2 PRAM1 Homo sapiens Q96QH2
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 PRAM1 Homo sapiens Q96QH2
Y2H Array
25416956
Intra CCDC57 Q2TAC2 PRAM1 Homo sapiens Q96QH2
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 ARL4A Homo sapiens P40617
Y2H Array
25416956
Intra CCDC57 Q2TAC2 ZGPAT Homo sapiens Q8N5A5
Y2H Array
25416956
Intra CCDC57 Q2TAC2 ZGPAT Homo sapiens Q8N5A5
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 NELFE Homo sapiens P18615
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 NELFE Homo sapiens P18615
Y2H Array
25416956
Intra CCDC57 Q2TAC2 PPHLN1 Homo sapiens Q8NEY8
Y2H Array
25416956
Intra CCDC57 Q2TAC2 NUMA1 Homo sapiens Q14980
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 NUMA1 Homo sapiens Q14980
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 NUMA1 Homo sapiens Q14980
Y2H Array
25416956
Intra CCDC57 Q2TAC2 CWF19L2 Homo sapiens Q2TBE0
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 CWF19L2 Homo sapiens Q2TBE0
Y2H Array
25416956
Intra CCDC57 Q2TAC2 FAM90A1 Homo sapiens Q86YD7
Y2H Array
25416956
Intra CCDC57 Q2TAC2 FAM90A1 Homo sapiens Q86YD7
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 CBX8 Homo sapiens Q9HC52
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 CBX8 Homo sapiens Q9HC52
Y2H Array
25416956
Intra CCDC57 Q2TAC2 HBA1 Homo sapiens P69905
Y2H Array
25416956
Intra CCDC57 Q2TAC2 TLE5 Homo sapiens Q08117
Y2H Array
25416956
Intra CCDC57 Q2TAC2 TLE5 Homo sapiens Q08117
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 FAM161A Homo sapiens Q3B820
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 FAM161A Homo sapiens Q3B820
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 LENG1 Homo sapiens Q96BZ8
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 FAM50B Homo sapiens Q9Y247
Y2H Array
25416956
Intra CCDC57 Q2TAC2 FAM50B Homo sapiens Q9Y247
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 USP2 Homo sapiens O75604
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 USP2 Homo sapiens O75604
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 USP2 Homo sapiens O75604
Y2H Array
25416956
Intra CCDC57 Q2TAC2 RAB3IL1 Homo sapiens Q8TBN0
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 AQP1 Homo sapiens P29972
Y2H Array
25416956
Intra CCDC57 Q2TAC2 AQP1 Homo sapiens P29972
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 GPKOW Homo sapiens Q92917
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 GPKOW Homo sapiens Q92917
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 TMEM100 Homo sapiens Q9NV29
Y2H Prey Pooling
25416956
Intra CCDC57 Q2TAC2 TMEM100 Homo sapiens Q9NV29
Y2H Array
25416956
Intra CCDC57 Q2TAC2 TBC1D22B Homo sapiens Q9NU19
Validated Y2H
25416956
Intra CCDC57 Q2TAC2 TBC1D22B Homo sapiens Q9NU19
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02050 CCDC57 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CCDC57 MGD MGI:1918526
Rattus norvegicus CCDC57 RGD RGD:1590047
Bos taurus CCDC57 VGNC VGNC:26901
Macaca mulatta CCDC57 VGNC VGNC:70882
Felis catus CCDC57 VGNC VGNC:82398
Canis familiaris CCDC57 VGNC VGNC:38843